2016
DOI: 10.1080/1744666x.2016.1195685
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Childhood-onset systemic lupus erythematosus: early disease manifestations that the paediatrician must know

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Cited by 35 publications
(50 citation statements)
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“…A similar observation was made by Hari et al (19) that more boys were found to be affected with stage IV nephritis. The clinical and laboratory features of lupus nephritis encountered in our study are broadly in conformity with other reports (20)(21)(22)(23). It has been the classical textbook teaching that SLE results in non-erosive arthritis; however, we found two children with deforming arthritis satisfying the rhupus syndrome designation and one with SLE and cutaneous scleroderma overlap syndrome (24,25).…”
Section: Discussionsupporting
confidence: 77%
“…A similar observation was made by Hari et al (19) that more boys were found to be affected with stage IV nephritis. The clinical and laboratory features of lupus nephritis encountered in our study are broadly in conformity with other reports (20)(21)(22)(23). It has been the classical textbook teaching that SLE results in non-erosive arthritis; however, we found two children with deforming arthritis satisfying the rhupus syndrome designation and one with SLE and cutaneous scleroderma overlap syndrome (24,25).…”
Section: Discussionsupporting
confidence: 77%
“…We have confirmed and extended previous observation that liver involvement is rarely observed in cSLE and adult SLE patients, with a variety of clinical and laboratorial manifestations [1,[12][13][14][15][16]. The rigorous selection criteria of AIH and cSLE patients excluding viral infections, malignancies and alcohol intake was relevant to avoid other confounding etiologies of hepatitis [1,7,12,14].…”
Section: Discussionsupporting
confidence: 85%
“…The most relevant issue observed by LAPR was the nonadherence of medication, in spite of high frequencies of glucorticosteroid, antimalarials, and immunosuppressive availability. Compliance is a determinant factor on cSLE outcome [26][27][28], and Brazilian Society of Rheumatology Consensus for SLE reinforced the importance to evaluate adherence in all appointments, especially for adolescents [29]. Furthermore, alcohol intake and illicit drug were also important issues evidenced in adolescents, particularly reported by LAPR in large centers.…”
Section: Discussionmentioning
confidence: 99%