Childhood teratomas in Ibadan, Nigeria

Outcome of management of complicated extragonadal teratoma in a resource poor setting

“…This has a bearing on the type of treatment. Most of the EXGT in our study were benign, which agreed with other previous study on teratoma in Nigeria [5] and would have benefited from early and complete removal as those that had malignant transformation might have been helped with a cure.…”

“…[5] EXGT histologically can be mature (benign), immature or endodermal sinus tumour. This has a bearing on the type of treatment.…”

“…[9,10] The female preponderance is still consistent with reports in other series. [5][6][7] The late presentation is as a result of inability to afford interventions offered at delivery, refusal of surgery because of lack of conviction of surgical intervention in neonates, prior excision by the untrained who did not even send specimen for histology and hidden tumour in some patients.…”

“…[2] Teratoma can occur in almost any region of the body and in any organ, but they are commonly observed in the paraxial and midline location. [5] The distribution of teratomas includes ovaries, testes, anterior mediastinum, retroperitoneum, presacral and coccygeal areas, pineal and other intracranial sites and neck. [6,7] Williams et al [8] showed that the neck is the second most common site after the sacrococcygeal region in Nigerian children.…”

Sacrococcygeal teratoma in Nigerians: A case report and clinico-pathologic review

“…Teratomas are tumors that arise from the proliferation of pluripotent stem cells which can differentiate into ectodermal, endodermal, and mesodermal derivatives in embryonic life [1,2]. These tumors occur in various gonadal and extragonadal regions, with Sacrococcygeal Teratomas (SCTs) being the most common extragonadal teratoma [2,3].…”