Childhood trauma and adult mental disorder: A systematic review and meta‐analysis of longitudinal cohort studies

McKay, Michael T.; Cannon, Mary; Chambers, Derek; Conroy, Ronán; Coughlan, Helen; Dodd, Philip; Healy, Colm; O’Donnell, L.; Clarke, Mary

doi:10.1111/acps.13268

Cited by 253 publications

(178 citation statements)

References 55 publications

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“…These findings underline and confirm what is extensively reported in literature; i.e., that early trauma deeply impacts on the development and severity of psychosis ( 64 ) ( Figure 2 ).…”

Section: Resultssupporting

confidence: 91%

Sexuality in Ultra-High Risk for Psychosis and First-Episode Psychosis. A Systematic Review of Literature

et al. 2021

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A considerable body of literature reports that individuals with psychotic disorders often suffer from sexual dysfunctions (SDs), with these representing a major unmet need. Long-term antipsychotic drug treatment may be the main cause for SDs in psychotic patients, through a plethora of different mechanisms, including prolactin dyscrasia, histamine-mediated sedation, and serotonin-induced sexual demotivation. However, a few pieces of evidence treat sexuality in patients at risk or the onset of psychosis. For this purpose, we systematically reviewed literature of the last 10 years in order to investigate sexuality in ultra-high risk (UHR) for psychosis and first-episode psychosis (FEP). We included in our review 34 articles fitting our research criteria on SDs in UHR and FEP. Evidence of SDs in the transition from UHR to FEP emerges through the selected studies. In FEP, sexuality is affected by the severity of the psychotic symptoms and, in some cases, by the iatrogenic effects of psychopharmacological treatment. Further experimental and clinical studies should systematically investigate the role of sexual functioning in the transition from UHR to FEP and, consequently, clarify whether or not SDs could be considered a possible marker for the onset of psychosis in at-risk populations. Moreover, psychiatrists and clinical psychologists should take into consideration the role of sexual life in young people with prodromal mental symptoms or at the onset of psychosis. Focusing on a thorough sexual evaluation might be a major challenge that could break down barriers of mental health promotion among young people with schizophrenia-spectrum disorders and therefore achieve better clinical outcomes.

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“…These findings underline and confirm what is extensively reported in literature; i.e., that early trauma deeply impacts on the development and severity of psychosis ( 64 ) ( Figure 2 ).…”

Section: Resultssupporting

confidence: 91%

Sexuality in Ultra-High Risk for Psychosis and First-Episode Psychosis. A Systematic Review of Literature

et al. 2021

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“…However, this type also includes some adulthood traumas such as rape and domestic violence that question the individual executive ownership of her/his body and self decision-making. Early childhood trauma is associated with adult mental disorders (for meta-analysis, see: McKay et al, 2021).…”

Section: Identity (Personal and Collective) Trauma Modelmentioning

confidence: 99%

The Development-Based Taxonomy of Stressors and Traumas: An Initial Empirical Validation

Kira¹

2021

PSYCH

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The development-based trauma framework (DBTF) proposed a comprehensive taxonomy of stressors and traumas based on the salience of existence and identity development. The goal of this research is to check the validity of some of the DBTF parameters, specifically the trauma types severity (Types I, II, and III), and the six major trauma types (attachment, personal identity, collective identity, role identity, survival and secondary traumas) differential impact and proliferation. We used a sample from 11 Arab countries (N = 2732), age ranged from 18 -91, mean = 26.9, and SD = 10.01, with 69.3% females. We used measures for cumulative stressors and traumas, PTSD, depression, anxiety, and executive functions. We conducted correlation and path analysis. Correlation explored the differential sizes of association between types I, II, III traumas and mental health and executive function deficits. Path analysis explored the proliferation of and paths between the six major types of trauma and their impact on mental health and cognitive functions. Results indicated that the size of associations of type III trauma and mental health and executive function variable were significantly larger than type II trauma and the same for the difference in the associations between type II and type I, which validate the differential intensity impact of trauma types. Results indicated that attachment traumas have the highest impact on other traumas, followed by early childhood adversities (personal identity trauma) and collective identity traumas, with differential impact on mental health and executive functions. The conceptual, trauma measurement and clinical implications of results were discussed.

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“…CM is associated with significantly increased risk of mental disorders during childhood, including posttraumatic stress disorder (PTSD), psychotic disorders, attention-deficit/hyperactivity disorder, anxiety and depressive disorders (12,13). CM is also associated with mental disorders in adolescence (14), and with impaired mental health (15) and dissociative symptoms in severe mental disorders such as schizophrenia, bipolar disorder and personality disorders in adulthood (16). In both low-and highincome countries, women exposed to CM are at increased risk of developing postpartum depression (17,18), which in turn increases the risk of impaired maternal-child attachment (19) and depression in the child (20).…”

Section: Effects Of Child Maltreatment On Mental and Physical Healthmentioning

confidence: 99%

Social functioning in individuals affected by childhood maltreatment: establishing a research agenda to inform interventions

Pfaltz¹,

Halligan²,

Haim-Nachum³

et al. 2021

Preprint

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In individuals with a history of child maltreatment (CM), impairments in many domains of social functioning are well-documented but poorly understood. We summarize evidence for the detrimental effects of CM on social functioning and present key research recommendations focused on: 1. Identifying alterations in specific inter- and intra- personal processes (e.g., regulation of closeness and distance) that underlie problems in broader domains of social functioning (e.g., lack of perceived social support) in individuals who have experienced CM; 2. Examining whether alterations in specific processes and their link to broader social problems are modulated by internal and external situational factors; 3. Assessing social processes through laboratory studies and in vivo interactive approaches; 4. Adopting an interdisciplinary, lifespan perspective to assess bio-behavioral and environmental effects of CM within and across generations, using multi-method assessments; 5. Establishing global research collaborations to account for cultural and ethnic influences on social processes. Understanding the mechanisms that underlie problems in social functioning, as well as cultural and ethnic influences, might inform the implementation of effective prevention programs. Moreover, the proposed research is critical to develop interventions that help affected individuals build stable and nurturing relationships. Such relationships can – likely through buffering the effects of chronic stress and corresponding allostatic load – foster resilience and improve mental and physical well-being, thereby reducing not only personal suffering but also the societal and economic costs of CM and its consequences.

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Childhood trauma and adult mental disorder: A systematic review and meta‐analysis of longitudinal cohort studies

Cited by 253 publications

References 55 publications

Sexuality in Ultra-High Risk for Psychosis and First-Episode Psychosis. A Systematic Review of Literature

Sexuality in Ultra-High Risk for Psychosis and First-Episode Psychosis. A Systematic Review of Literature

The Development-Based Taxonomy of Stressors and Traumas: An Initial Empirical Validation

Social functioning in individuals affected by childhood maltreatment: establishing a research agenda to inform interventions

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