Childhood trauma predicts multiple, high lethality suicide attempts in patients with schizophrenia

Alli, Sauliha; Tasmim, Samia; Adanty, Christopher; Graff, Ariel; Strauss, John S.; Zai, Clement C.; Gerretsen, Philip; Borlido, Carol; Luca, Vincenzo De

doi:10.1016/j.psychres.2019.112567

Cited by 10 publications

(3 citation statements)

References 33 publications

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“…Scholars also found that all ages are at risk for suicide. Suicidal ideation and behavior are relatively common in healthy, It is worth noting that more than 90% of victims of suicide have a psychiatric disorder ( 23 ), in addition, a history of child trauma may lead to increased risk for psychiatric symptoms ( 29 ) and suicidal attempt in the SCZ ( 33 ). However, more recent research explored the heterogeneity in the relationship between child trauma and psychotic symptoms, a study of large population-based sample discovered intention to harm is the key factor linking child trauma and general psychopathology symptoms of hallucinations and delusions, rather than specific psychotic symptoms in isolation, these finding are consistent with present study, furthermore, no evidence supported that the specific type of child trauma had associations between with particular psychotic symptoms ( 30 ).…”

Section: Discussionmentioning

confidence: 99%

Childhood maltreatment increases the suicidal risk in Chinese schizophrenia patients

Cheng

Ju²,

Xia³

et al. 2022

Front. Psychiatry

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ObjectivesChildhood trauma might be a modifiable risk factor among adults with serious mental illness. However, the correlation of child trauma and suicide is unclear, which were cited most frequently as the biggest challenge to schizophrenia (SCZ) patients in China. We aim to study relationships between child trauma and suicide in SCZ patients of different disease stages.MethodsNinety-one participants were included and divided into two groups, namely, first-episode group (n = 46), relapsed group (n = 45). The Positive and Negative Syndrome Scale was used to evaluate the severity of psychotic symptoms. The Beck's Suicide Intent Scale and The Nurses' Global Assessment of Suicide Risk were conducted by patient self-report to assess suicide symptom. The childhood trauma questionnaire was used to estimate severity of traumatic stress experienced during childhood.ResultsChildhood trauma and different dimensions of suicide were significantly higher in the relapsed group than first-episode group (P < 0.01, respectively). BMI has a significant positive relationship with recent psychosocial stress (β = 0.473, t = 3.521, P < 0.001) in first-episode group. As in relapsed group, BMI has a positive effect between severe mental illness and suicide ideation (β = 0.672, t = 5.949, P < 0.001; β = 0.909, t = 2.463, P < 0.001), Furthermore, emotional neglect presented positively related to the suicide risk and proneness to suicidal behavior (β = 0.618, t = 5.518, P < 0.001; β = 0.809, t = 5.356, P < 0.001).ConclusionRelapsed group of patients had significantly more severe childhood trauma, recent psychosocial stress, suicidal risk and proneness to suicidal behavior. BMI and emotional neglect are unique predictors for different dimensions of suicide.

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Section: Discussionmentioning

confidence: 99%

Childhood maltreatment increases the suicidal risk in Chinese schizophrenia patients

Cheng

Ju²,

Xia³

et al. 2022

Front. Psychiatry

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“…However, previous studies on the relationship between CT and suicide in schizophrenia have been inconsistent. Some research shows that CT has nothing to do with attempted suicide in schizophrenia (16), but other studies have found that CT is a strong predictor of suicide in schizophrenia (17)(18)(19). Further studies find that suicide attempts are associated with all CT dimensions, such as physical, sexual, psychological abuse, and neglect, except for physical neglect (20), while other studies find that physical neglect and sexual abuse are indeed associated (21,22).…”

Section: Introductionmentioning

confidence: 99%

Childhood Trauma and Insomnia Increase Suicidal Ideation in Schizophrenia Patients: A Cross-Sectional Study

et al. 2021

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Objectives: This study aimed to investigate the effect of childhood trauma, especially its specific dimensions, and clinical risk factors for suicidal ideation in patients with schizophrenia.Methods: A total of 83 inpatients with schizophrenia were enrolled and divided into two groups: with suicidal ideation (n = 33) and without suicidal ideation (n = 50). All participants were administered the Childhood Trauma Questionnaire-Short Form, the Insomnia Severity Index, the Beck Scale for Suicide Ideation, the Modified Overt Aggression Scales, the auditory hallucination rating scale, the Hamilton Rating Scale of Depression and the Positive and Negative Syndrome Scale.Results: In our sample, 39.8% of the subjects had suicidal ideation, and 60.6% of them had suffered from childhood trauma. Patients with suicidal ideation had a higher Insomnia Severity Index score, Physical neglect score, the Childhood Trauma Questionnaire-Short Form total score (all P < 0.05) compared to those without. The logistic regression analysis revealed that physical neglect in Childhood Trauma Questionnaire was significantly associated with suicidal ideation (OR = 5.46, P < 0.05, 95% CI = 0.007–0.483). Further stepwise multiple linear regression identified that insomnia (β = 0.272, P = 0.011) and physical neglect (β = 0.257, P = 0.017) were strong risk factors for the severity of suicidal ideation in patients with schizophrenia. Mediation analysis showed that insomnia played a complete mediating role between physical neglect and suicidal ideation.Conclusion: Our results indicate that childhood maltreatment of physical neglect is a strong independent risk factor for suicidal ideation in schizophrenia. The risk is probably aggravated by the poor quality of sleep. Early screening and psychosocial treatment are recommended for psychotic individuals with a trauma history.

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“…Childhood trauma has been established as a risk factor for the development of and various impacts of psychosis (Baumeister et al, 2014;Carr et al, 2013;Lardinois et al, 2011;Mondelli et al, 2015;Read et al, 2005;Stanton et al, 2020;Varese et al, 2012); however, the literature is mixed on what types of trauma increase suicidal risk. Studies using the Childhood Trauma Questionnaire (CTQ; Bernstein et al, 1997Bernstein et al, , 2003-a standard in the field-show differential findings between the association of trauma subtypes (emotional abuse, emotional neglect, physical abuse, physical neglect, and sexual abuse) and increased risk for SI (Cui et al, 2019;Grattan et al, 2019;Xie et al, 2018), suicide attempts (SAs; Hassan et al, 2016;Mohammadzadeh et al, 2019;Roy, 2005), and the lethality of SAs (Alli et al, 2019). Turning to well-studied theories of suicide, such as the interpersonal psychological theory of suicide (IPTS), and wellstudied constructs in suicide may help bridge the gap to explain the mixed literature on trauma type and their corresponding association with suicidal thoughts and behaviors in this population.…”

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confidence: 99%

Childhood Trauma Associations With the Interpersonal Psychological Theory of Suicide and Social Cognitive Biases in Psychotic Disorders

et al. 2021

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Childhood trauma (CT) is associated with suicidal ideation and behaviors (SI/SB) in people with psychosis. The interpersonal psychological theory of suicide (IPTS) suggests that there are four factors that increase suicide risk: thwarted belongingness, perceived burdensomeness, acquired capacity for suicide, and hopelessness. The IPTS constructs and social cognitive biases are associated with SI/SB in psychotic disorders. However, the role of CT in IPTS constructs and social cognitive biases has not been examined in psychosis. In an outpatient community sample of persons with psychotic disorders (N = 96) assessed with the Childhood Trauma Questionnaire, the aims of this study were to a) evaluate rates of CT in this sample, b) determine the relationship between CT types and lifetime SI/SB, and c) explore the relationship between CT types, IPTS constructs, and social cognitive biases. All participants reported experiencing CT. Emotional abuse was associated with greater SI severity and higher rates of lifetime suicide attempts, as well as with greater perceived burdensomeness and more severe negative social cognitive biases. Other CT types were minimally associated with SI/SB or IPST constructs; hopelessness was not associated. Overall, negative interpersonal beliefs and social cognitive biases may explain how CT increases suicide risk in psychosis.

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Childhood trauma predicts multiple, high lethality suicide attempts in patients with schizophrenia

Cited by 10 publications

References 33 publications

Childhood maltreatment increases the suicidal risk in Chinese schizophrenia patients

Childhood maltreatment increases the suicidal risk in Chinese schizophrenia patients

Childhood Trauma and Insomnia Increase Suicidal Ideation in Schizophrenia Patients: A Cross-Sectional Study

Childhood Trauma Associations With the Interpersonal Psychological Theory of Suicide and Social Cognitive Biases in Psychotic Disorders

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