Children’s Health Centers: Past, Present, and Future

Spivey, Angela

doi:10.1289/ehp.115-a192

Cited by 7 publications

(6 citation statements)

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“…The EPA has identified 3,000 high-production-volume (HPV) chemicals [23] and the European Union has established the Registration, Evaluation, Authorization and Restriction of Chemical substances (REACH) to protect human health and to evaluate the hazards that are posed by synthetic chemicals. [24] However, these risk assessment and the determination of toxic concentrations are mostly defined for adults, despite the fact that children are clearly exposed to toxic chemicals in the environment at higher levels because of their inherent susceptibility (i.e.…”

Section: Discussionmentioning

confidence: 99%

Inhalation Toxicity of Humidifier Disinfectants as a Risk Factor of Children’s Interstitial Lung Disease in Korea: A Case-Control Study

Yang

Kim

et al. 2013

PLoS ONE

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BackgroundThe occurrence of numerous cases of interstitial lung disease in children (chILD) every spring in Korea starting in 2006 raised suspicion about a causal relationship with the use of humidifier disinfectants (HDs). The aim of this study was to evaluate the association between HD use and the risk of chILD.MethodsThis retrospective, 1∶3 matched case-control study consisted of 16 cases of chILD that had developed between 2010 and 2011. The three groups of parallel controls (patients with acute lobar pneumonia, asthma, and healthy children) were matched by age, gender, and index date. Indoor/outdoor environmental risk factors, including HD use, were investigated by asking the guardians to complete a questionnaire.ResultsThe median age of the affected children (43.8% male) was 26 months (18.25–36.25). The chILD group did not differ significantly from the control groups with respect to socio-demographic and clinical variables. Indoor and outdoor environmental factors were not associated with a risk of chILD. However, the previous use of HDs (OR; 2.73. 95% CI; 1.41–5.90, P = 0.00) were independently associated with an increased risk.ConclusionsThis study showed that HDs, which are widely used in South Korea in the winter season, independently increased the risk of chILD in spring. Therefore, continuous monitoring and, if needed, changes in policy are essential to prevent and control pediatric diseases caused by toxic chemicals.

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Section: Discussionmentioning

confidence: 99%

Inhalation Toxicity of Humidifier Disinfectants as a Risk Factor of Children’s Interstitial Lung Disease in Korea: A Case-Control Study

Yang

Kim

et al. 2013

PLoS ONE

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“…14,55,56 Such research, which includes epidemiologic monitoring of exposed populations as well as specific studies of the effects of particular chemicals, is an essential complement to toxicity testing. It provides direct evidence of the effects of chemicals on human health.…”

Section: May 2011 30:5 Health Affairsmentioning

confidence: 99%

Children’s Vulnerability To Toxic Chemicals: A Challenge And Opportunity To Strengthen Health And Environmental Policy

2011

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A key policy breakthrough occurred nearly twenty years ago with the discovery that children are far more sensitive than adults to toxic chemicals in the environment. This finding led to the recognition that chemical exposures early in life are significant and preventable causes of disease in children and adults. We review this knowledge and recommend a new policy to regulate industrial and consumer chemicals that will protect the health of children and all Americans, prevent disease, and reduce health care costs. The linchpins of a new US chemical policy will be: first, a legally mandated requirement to test the toxicity of chemicals already in commerce, prioritizing chemicals in the widest use, and incorporating new assessment technologies; second, a tiered approach to premarket evaluation of new chemicals; and third, epidemiologic monitoring and focused health studies of exposed populations.

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“…These scientific initiatives have generated new knowledge of early‐life exposures and their impacts on health. They include: Formation of a national network of Centers for Children's Environmental Health and Disease Prevention Research supported jointly by the National Institute of Environmental Health Sciences and the EPA 2 A global network of Pediatric Environmental Health Specialty Units supported by the CDC/Agency for Toxic Substances and Disease Registry 3…”

Section: Children's Vulnerability To Toxic Chemicalsmentioning

confidence: 99%

“…Research investment in environmental pediatrics has increased sharply in the past decade. Fourteen Centers for Children's Environmental Health and Disease Prevention Research have been established by the National Institutes of Health and the US Environmental Protection Agency (EPA) 2. The Centers for Disease Control and Prevention (CDC) has created a network of clinically oriented centers, Pediatric Environmental Health Specialty Units, that span the United States and now extend overseas 3.…”

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confidence: 99%

Children's Health and the Environment: An Overview

Landrigan

Miodovnik

2011

Mount Sinai J Medicine

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Environmental pediatrics, the branch of pediatric medicine that studies the influence of the environment on children's health, has in the past decade grown exponentially. Rising rates of pediatric chronic disease and growing recognition of children's extensive exposures and great vulnerabilities to toxic hazards in the environment have catalyzed this expansion. New scientific initiatives have resulted. They include 14 Centers for Children's Environmental Health and Disease Prevention Research supported by the US National Institutes of Health and the US Environmental Protection Agency; a global network of Pediatric Environmental Health Specialty Units supported by the US Centers for Disease Control and Prevention/Agency for Toxic Substances and Disease Registry; new postdoctoral training programs in pediatric environmental medicine; and the National Children's Study, the largest prospective epidemiological study of children's health ever undertaken in the United States, which launched in 2009 and will follow 100,000 children from conception to age 21 to assess environmental influences on health and development. These research initiatives have delineated the exquisite vulnerability of fetuses, infants, and children to toxic hazards in the environment. They have led to discovery of new environmental causes of disease and disability in children. This issue of The Mount Sinai Journal of Medicine focuses on children's health and the environment. We have brought together thought leaders in children's environmental health to critically examine new research findings, to explore new opportunities for translating research to treatment and prevention, and to offer a vision for the future of this rapidly expanding field.

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Children’s Health Centers: Past, Present, and Future

Cited by 7 publications

References 0 publications

Inhalation Toxicity of Humidifier Disinfectants as a Risk Factor of Children’s Interstitial Lung Disease in Korea: A Case-Control Study

Inhalation Toxicity of Humidifier Disinfectants as a Risk Factor of Children’s Interstitial Lung Disease in Korea: A Case-Control Study

Children’s Vulnerability To Toxic Chemicals: A Challenge And Opportunity To Strengthen Health And Environmental Policy

Children's Health and the Environment: An Overview

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