Children with Warts: A Retrospective Study in an Outpatient Setting

Kuwabara, Anne; Rainer, Barbara M.; Basdag, Hatice; Cohen, Bernard A.

doi:10.1111/pde.12584

Cited by 26 publications

(27 citation statements)

References 8 publications

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“…[19][20][21][22][23] • Clearance rates: 51.6% over 13 wks-68.2% over 3 mo. 9,14,17,[24][25][26][27] • Clearance rates of plantar warts is generally lower than warts at other sites. 9,27 • Pain and blistering.…”

Section: Cryotherapymentioning

confidence: 99%

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Treatment of cutaneous viral warts in children: A review

Soenjoyo

Chua

Wee

et al. 2020

Dermatologic Therapy

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Viral warts or verruca are very common skin infections in children. Although benign, lesions can be extensive, painful, bleed, or lead to cosmetic disfigurement. Although spontaneous resolution can occur, parents often bring their children for treatment, especially when they are symptomatic. Many publications have assessed the efficacy and safety of treatment of warts in adults. However, treatment in children can be challenging due to their immune responses and lower threshold for pain. We review the current literature on the methods, efficacy, and side effect profile of common treatment modalities for cutaneous viral warts in children. There is evidence that salicylic acid and cryotherapy are effective, and although cryotherapy is more effective, there is a higher risk of side effects such as pain and blistering. Combination treatment with salicylic acid and cryotherapy may reduce these side effects. Although there is limited data, other treatment options such as cantharidin, immunotherapy and other mechanical therapies, for example, carbon dioxide lasers, may also be considered, especially for recalcitrant lesions.

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Section: Cryotherapymentioning

confidence: 99%

“…• 18% at 6 mo to close to 100% at 2 yr. 9,11,14,17 Clearance rates of SA combination therapies • SA and glycolic acid: 100% over 8…”

Section: Cryotherapymentioning

confidence: 99%

Treatment of cutaneous viral warts in children: A review

Soenjoyo

Chua

Wee

et al. 2020

Dermatologic Therapy

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“…Warts are benign mucocutaneous tumors caused by the human papillomavirus (HPV). They are extremely common in the pediatric population, with a prevalence of 5%‐10% . While two‐thirds of warts generally resolve without treatment within a 2‐year period, they can be associated with significant irritation, pain, and psychosocial sequelae; therefore, treatment is often pursued.…”

Section: Introductionmentioning

confidence: 99%

Sinecatechins ointment for the treatment of warts in children

Deeb

Levy

Pope

et al. 2018

Pediatric Dermatology

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“…Acetic acid, particularly apple cider vinegar (ACV), is prominent among emerging natural remedies used by patients who seek therapies perceived as “safer” and “more natural” than prescriptions such as topical steroids . Patients currently use ACV for skin infections and other maladies ranging from common warts to AD . Even some dermatologists have recently started recommending ACV baths for AD .…”

Section: Introductionmentioning

confidence: 99%

“…9 Patients currently use ACV for skin infections and other maladies ranging from common warts to AD. 8,10 Even some dermatologists have recently started recommending ACV baths for AD. 9 ACV soaks are theoretically appealing given their antimicrobial activity and potential to acidify the skin.…”

Section: Introductionmentioning

confidence: 99%

Apple cider vinegar soaks [0.5%] as a treatment for atopic dermatitis do not improve skin barrier integrity

Luu

Flowers

Kellams

et al. 2019

Pediatric Dermatology

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Background/Objectives Atopic dermatitis (AD) is a common chronic inflammatory skin condition associated with high transepidermal water loss, high skin pH, and Staphylococcus aureus skin colonization. The treatment of AD with bath additives remains highly debated. Recent evidence suggests that dilute apple cider vinegar (ACV) may improve skin barrier integrity in AD, but its safety and efficacy are not well studied. This pilot split‐arm study analyzed the effect of dilute apple cider vinegar soaks on skin barrier integrity in patients with atopic dermatitis as measured by skin transepidermal water loss and skin pH. Methods A total of 22 subjects (11 AD and 11 healthy controls) were enrolled. Subjects soaked both of their forearms for 14 days, with one arm in dilute ACV (0.5% acetic acid) and the other in water 10 minutes daily. Transepidermal water loss and pH were measured pre‐ and post‐treatment. Results In both groups, transepidermal water loss increased and pH decreased at 0 minutes post‐ACV treatment, but these effects were not sustained at 60 minutes. In total, 72.7% (16/22) of subjects reported mild side effects from ACV with improvement after discontinuing the soaks. Conclusions Dilute ACV soaks have no significant effect on skin barrier integrity but caused skin irritation in a majority of subjects. Study limitations include analysis of a single brand, dilution, and application of ACV. Future studies are needed to explore whether lower concentrations of ACV soaks or other applications such as a leave‐on acidic ointment could improve skin barrier integrity in a safe, nonirritating way.

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Children with Warts: A Retrospective Study in an Outpatient Setting

Cited by 26 publications

References 8 publications

Treatment of cutaneous viral warts in children: A review

Treatment of cutaneous viral warts in children: A review

Sinecatechins ointment for the treatment of warts in children

Apple cider vinegar soaks [0.5%] as a treatment for atopic dermatitis do not improve skin barrier integrity

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