Chinese herbal medicines for the treatment of neonatal jaundice

There is no evidence that IV fluid supplementation affects important clinical outcomes such as bilirubin encephalopathy, kernicterus, or cerebral palsy in healthy, term newborn infants with unconjugated hyperbilirubinaemia requiring phototherapy. In this review, no infant developed these bilirubin-associated clinical complications. Low- to moderate-quality evidence shows that there are differences in total serum bilirubin levels between fluid-supplemented and control groups at some time points but not at others, the clinical significance of which is uncertain. There is no evidence of a difference between the effectiveness of IV and oral fluid supplementations in reducing serum bilirubin. Similarly, no infant developed adverse events or complications from fluid supplementation such as vomiting or abdominal distension. This suggests a need for future research to focus on different population groups with possibly higher baseline risks of bilirubin-related neurological complications, such as preterm or low birthweight infants, infants with haemolytic hyperbilirubinaemia, as well as infants with dehydration for comparison of different fluid supplementation regimen.

show abstract

Chinese herbal medicines for the treatment of neonatal jaundice

Cited by 2 publications

References 23 publications

Fluid supplementation for neonatal unconjugated hyperbilirubinaemia

Fluid supplementation for neonatal unconjugated hyperbilirubinaemia

Fluid supplementation for neonatal unconjugated hyperbilirubinaemia

Contact Info

Product

Resources

About