The article analyzes changes in the activities of transnational banks (TNBs) taking into account the consequences of the coronavirus pandemic. A review of modern literature on the subject under study was carried out. Given the importance of TNBs for many countries, understanding the scope and direction of current changes is of particular importance to the global economy. Over the past two decades, transnational banking has experienced the following trends: the transformation of credit strategies from aggressive to conservative; South-South banking growth; access to alternative sources of financing; a significant increase in the size of banks; expansion of Chinese banks; strengthening the position of fast-growing markets as home countries of TNBs and the growing importance of developing and emerging markets as host countries of TNBs; geographical differentiation and regionalization of their activities. The results of the study show that the above-mentioned trends are due to a decline in the economies of developed countries and an increase in the economic importance of developing countries. Based on this, we predict a low probability that developed country banks will be active creditors in the near future. Banks from developing countries (especially within their geographical region), whose financial position is much better, can be of great importance in this capacity. It is expected that 2020 will be the year of turning points in the development of transnational banking. A decade after the global economic crisis of 2008-2009, the banking industry faces a new problem that has undoubtedly affected almost every sector of the world economy - the outbreak of coronavirus. Given the lack of research on this topic, the article comprehensively examines the consequences of the crisis pandemic for TNBs.