Chinese Patent Medicines in the Treatment of Coronavirus Disease 2019 (COVID-19) in China

Zhuang, Wei; Fan, Zheng; Chu, Yanqi; Wang, Haizheng; Yang, Ying; Wu, Li; Sun, Nan; Sun, Ge; Shen, Yuqiao; Lin, Xiaolan; Guo, Guiming; Xi, Shengyan

doi:10.3389/fphar.2020.01066

Cited by 83 publications

(74 citation statements)

References 124 publications

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“…Nowadays, traditional Chinese patent medicines (CPMs) that contain various natural compounds have been used to treat COVID-19 to prevent virus, inflammation and lung injury. These CPMs such as Tanreqing injection (TRQI), Lianhua Qingwen capsule (LHQWC) and Xuebijing injection (XBJI) have good therapeutic efficacy in COVID-19 treatment [ 420 ].…”

Section: Potential Clinical Use Of Natural Compounds For Alimentioning

confidence: 99%

Natural product derived phytochemicals in managing acute lung injury by multiple mechanisms

Zhou

et al. 2021

Pharmacological Research

251

121

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Section: Potential Clinical Use Of Natural Compounds For Alimentioning

confidence: 99%

Natural product derived phytochemicals in managing acute lung injury by multiple mechanisms

Zhou

et al. 2021

Pharmacological Research

251

121

View full text Add to dashboard Cite

show abstract

“…Furthermore, there are many other proprietary traditional Chinese medicine products also play an important therapeutic role by direct antiviral actions, antipyretic and analgesic, immune-regulation, antiinflammation, and anti-acute lung injury, such as Agastache Qi-Correcting Capsule (Huoxiang Zhengqi Jiaonang), Lonicera Fever-clearing Granule (Jinhua Qinggan Keli), Wind-scattering Toxin-resolving Capsule (Shufeng Jiedu Jiaonang), Xiyanping Injection (Xiyanping Zhusheye), Blood-clearing Injection (Xuebijing Zhusheye), Ginseng and Aconite Injection (Shenfu Zhusheye), Ginseng and Ophiopogon Injection (Shenmai Zhusheye), Peaceful Palace Bovine Bezoar Pill (Angong Niuhuang Wan), etc. (Zhuang et al, 2020).…”

Section: Tcm For the Treatment Of Coronavirus Induced Disease 2019 (Cmentioning

confidence: 99%

Role of Traditional Chinese Medicine in the Management of Viral Pneumonia

Yue

et al. 2020

Front. Pharmacol.

Self Cite

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Viral pneumonia is one kind of acute respiratory tract infection caused by the virus. There have been many outbreaks of viral pneumonia with high contagiousness and mortality both in China and abroad, such as the great influenza in 1918, the severe acute respiratory syndrome (SARS) coronavirus in 2003, the Influenza A (H1N1) virus in 2009, and the Middle East Respiratory Syndrome coronavirus (MERS-CoV) in 2012 and the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in 2019. These outbreaks and/ or pandemic have significant impact on human life, social behaviors, and economic development. Moreover, no specific drug has been developed for these viruses. Traditional Chinese medicine (TCM) plays an important role in the treatment of viral pneumonia during these outbreaks especially in SARS and SARS-CoV-2 because studies suggest that TCM formulations may target several aspects of the disease and may have lesser side effects than manufactured pharmaceuticals. In recent years, a lot of clinicians and researchers have made a series of in-depth explorations and investigations on the treatment of viral pneumonia with TCM, which have understood TCM therapeutic mechanisms more specifically and clearly. But critical analysis of this research in addition to further studies are needed to assess the potential of TCM in the treatment of viral pneumonia.

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“…The WHO proposed A. annua as a possible treatment to be considered for COVID-19 treatment, however its efficacy and side-effects must be determined. Additionally, A. annua is one of the of Jinhua Qinggan granule ingredients, one of the Traditional Chinese Patent Medicines recommended in 13 therapeutic regimens of COVID-19 in China [ 305 ]. The A. argyi it was also mentioned as one of the plants that can be used by aromatherapy method of Traditional Chinese Medicine with effects of contagion prevention [ 306 ].…”

Section: Hotpoint Research: Artemisia Species Amentioning

confidence: 99%

Research Advances on Health Effects of Edible Artemisia Species and Some Sesquiterpene Lactones Constituents

Трендафилова

Moujir

Sousa

et al. 2020

Foods

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The genus Artemisia, often known collectively as “wormwood”, has aroused great interest in the scientific community, pharmaceutical and food industries, generating many studies on the most varied aspects of these plants. In this review, the most recent evidence on health effects of edible Artemisia species and some of its constituents are presented and discussed, based on studies published until 2020, available in the Scopus, Web of Sciences and PubMed databases, related to food applications, nutritional and sesquiterpene lactones composition, and their therapeutic effects supported by in vivo and clinical studies. The analysis of more than 300 selected articles highlights the beneficial effect on health and the high clinical relevance of several Artemisia species besides some sesquiterpene lactones constituents and their derivatives. From an integrated perspective, as it includes therapeutic and nutritional properties, without ignoring some adverse effects described in the literature, this review shows the great potential of Artemisia plants and some of their constituents as dietary supplements, functional foods and as the source of new, more efficient, and safe medicines. Despite all the benefits demonstrated, some gaps need to be filled, mainly related to the use of raw Artemisia extracts, such as its standardization and clinical trials on adverse effects and its health care efficacy.

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Chinese Patent Medicines in the Treatment of Coronavirus Disease 2019 (COVID-19) in China

Cited by 83 publications

References 124 publications

Natural product derived phytochemicals in managing acute lung injury by multiple mechanisms

Natural product derived phytochemicals in managing acute lung injury by multiple mechanisms

Role of Traditional Chinese Medicine in the Management of Viral Pneumonia

Research Advances on Health Effects of Edible Artemisia Species and Some Sesquiterpene Lactones Constituents

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