2023
DOI: 10.1088/1361-6528/acae5c
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Chip for dielectrophoretic microbial capture, separation and detection I: theoretical basis of electrode design

Abstract: We model the dielectrophoretic response of E. coli bacterial cells and red blood cells, upon exposure to an electric field. We model the separation, capture, and release mechanisms under flow conditions in a microfluidic channel and show under which conditions efficient separation of different cell types occur. The modelling work is aimed to guide the separation electrode architecture and design for experimental validation of the model. The dielectrophoretic force is affected both by the geometry of the electr… Show more

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Cited by 3 publications
(8 citation statements)
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“…The DEP force calculated from bacterial capture under flow conditions as shown above gives a DEP force value of the same order of magnitude as obtained using COMSOL simulations shown in in our theoretical work accompanying this paper [10]. This validates our model presented before that was initially used for estimated the DEP force and optimizing electrode system design [10].…”
Section: Kinetics Of Bacteria Capture On the Ring Electrode Systemsupporting
confidence: 81%
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“…The DEP force calculated from bacterial capture under flow conditions as shown above gives a DEP force value of the same order of magnitude as obtained using COMSOL simulations shown in in our theoretical work accompanying this paper [10]. This validates our model presented before that was initially used for estimated the DEP force and optimizing electrode system design [10].…”
Section: Kinetics Of Bacteria Capture On the Ring Electrode Systemsupporting
confidence: 81%
“…To explain the experimental findings, the dielectrophoresis force acting on bacteria in a microfluidic channel was simulated using COMSOL Multiphysics (see also companion paper in the same issue [10]). Figure 9(a) shows the microchannel cross section and the simulated dielectrophoresis force acting on an E. coli bacterium (gray).…”
Section: Dep Depletion Zone and Ac Kinetic Forces Acting On Particles...mentioning
confidence: 99%
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“…M Weber, a former member, contributed a series of articles on the theoretical and experimental studies of dielectrophoretic capture and detection of microbial cells [9,10], W Guan, a former member, wrote an article on modeling study of pyramidal silicon nanopores which can be an effective analytical tool for ion transport [11], Y Jung, also a former member, wrote an article on vertically aligned twodimensional (2D) molybdenum disulfide (MoS 2 ) layers for gas sensors [12]. And, M S Strano, a collaborator with Mark Reed, contributed an article on 2D hexagonal boron nitride (hBN) for quantum emission [13].…”
mentioning
confidence: 99%