Chiral Quadridentate Ligands Derived from Amino Acids and Some Zinc Complexes Thereof

Spectroscopic Properties, Electrochemistry, and Reactivity of Mo0, MoI, and MoII Complexes with the [Mo(bpa)(CO)3] Unit [bpa = bis(2-picolyl)amine] and Their Application for the Labelling of Peptides

“…All analytical data supported the proposed constitution and underscore the potential of the Mo-(bpa)(CO) 3 group as a robust marker group in bioorganometallic chemistry. Moreover, in contrast to tacn and hydridotrispyrazolylborate, the bpa ligand can easily be derivatized with a (protected) acid functionality, [10,11] which makes binding to biomolecules possible. [7Ϫ9] However, perhaps the most obvious low-valent Mo fragment is fac-Mo(CO) 3 , in the form of octahedral [L 3 Mo(CO) 3 ] complexes.…”

“…( Wiley-VCH Verlag GmbH, 69451 Weinheim, Germany, 2002) cently introduced the versatile and robust Mo(allyl)(CO) 2 moiety as a marker group in bioorganometallic chemistry. [11,12] The ligand bpa, first reported by Romary et al, [13] is one of the classical tridentate nitrogen donor ligands in coordination chemistry, but (bpa)metal complexes containing organometallic fragments are relatively scarce. For biological applications, the ligand L 3 must fulfil several requirements.…”

Spectroscopic Properties, Electrochemistry, and Reactivity of Mo0, MoI, and MoII Complexes with the [Mo(bpa)(CO)3] Unit [bpa = bis(2-picolyl)amine] and Their Application for the Labelling of Peptides

“…We propose the bis(2-picolyl)amine ligand [bis(picolyl)amine, bpa] as an interesting alternative, because its Mo(CO) 3 complexes are readily accessible and very stable, as shown here. Moreover, in contrast to tacn and hydridotrispyrazolylborate, the bpa ligand can easily be derivatized with a (protected) acid functionality, [10,11] which makes binding to biomolecules possible. [11,12] The ligand bpa, first reported by Romary et al, [13] is one of the classical tridentate nitrogen donor ligands in coordination chemistry, but (bpa)metal complexes containing organometallic fragments are relatively scarce.…”

“…Moreover, in contrast to tacn and hydridotrispyrazolylborate, the bpa ligand can easily be derivatized with a (protected) acid functionality, [10,11] which makes binding to biomolecules possible. [11,12] The ligand bpa, first reported by Romary et al, [13] is one of the classical tridentate nitrogen donor ligands in coordination chemistry, but (bpa)metal complexes containing organometallic fragments are relatively scarce. Only four organometallic bpa complexes have so far been structurally characterized by X-ray crystallography: namely, [Rh-(bpa)(cod)]BPh 4 [cod ϭ (Z,Z)-1,5-cyclooctadiene], [14] [Pt(bpa)CH 3 ]Cl, [15] [Pt(bpa)(η 1 -allyl)(CH 3 ) 2 ]Br, [15] and [W(bpa)(η 3 -allyl)(CO) 2 ]PF 6 .…”

Intramolecular ether oxygen coordination in the zinc complexes with dipicolylamine (DPA)-derived ligands

“…Thus, a lot of fluorescent zinc sensor molecules having DPA unit as a zinc-binding site have been reported [18][19][20][21]. Multidental nitrogen and oxygen ligands bound to zinc center have been investigated within the field of bioinorganic chemistry [22][23][24]. Zinc-DPA complex is also used as model complexes of hydrolytic enzymes of phosphate esters including nucleic acids [25,26].…”