Chirality of organophosphorus pesticides: Analysis and toxicity

The Development and Application of Cellulose-Based Stationary Phases in Stereoselective Separation of Chiral Pesticides

“…In recent years, cellulose-based CSPs prepared with different cellulose derivatives and methods resulted in their very broad application for chiral separation of pesticides such as organophosphates [38], organochlorine, triazole, synthetic pyrethroids, acylanilides, imidazolinones, phenoxypropanoic-acid herbicides and related compounds [39]. Table 2 summarizes the resolution results of 79 chiral pesticides in current references.…”

Isomerization of chiral pesticides in the environment

“…Diastereomers having different molecular properties can be resolved by usual chromatographic techniques, while enantiomers can be resolved only by using the specific column with a chiral stationary phase. 2,[9][10][11] There are three types of techniques for chiral separation, gas chromatography (GC), high-performance liquid chromatography (HPLC) and capillary electrophoresis (CE) in connection with high-sensitivity detectors represented by mass spectrometry (MS). 10,12,13) Many kinds of detectors are available for the chiral GC suitable for analysis of thermally stable pesticides, but the development of appropriate clean-up procedures or derivatization methods for polar metabolites is necessary.…”

“…[16][17][18] The enantioselectivity in biological systems has been identified first in the efficacy and mammalian toxicity of chiral pesticides, 1,19) and recently in their environmental fate 2,21,23) and ecotoxicological effects. 4,6,9,11,20) Specific stereoisomer(s) would then be enriched in the natural environment by the different rates of degradation among them. [21][22][23] The use of each stereoisomer is indispensable to examine the enantioselectivity of a chiral pesticide, especially when isomerization among stereoisomers occurs.…”

Enantioselective separation and determination of the dinotefuran enantiomers in rice, tomato and apple by HPLC

“…Capillary electrophoresis (CE) has also been explored and has shown a great potential for enantiomer resolution due to its high separation efficiency, versatility and low consumption of chiral selectors [7,8]. However, GC is primarily used in the analysis of volatile and thermally [9]. Another major disadvantage of CE is that unlike HPLC, it cannot be coupled with optical detectors (e.g.…”