Chirurgie der Iris und des Ziliarkörpers

Mackensen, G

doi:10.1007/978-3-642-72939-3_12

Cited by 2 publications

(2 citation statements)

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“…As in the case presented here, clinical symptoms may include evidence of a retrocorneal membrane; painful corneal decompensation; secondary glaucoma with angle closure; pupillary block; tractional retinal detachment; and ultimately loss of vision. For this reason, extensive epithelial downgrowth must be regarded and treated as a malignant condition [3]. This is caused by progressive single-to multi-layered growth of rapidly proliferating epithelial cells on the posterior sur-face of the cornea; across the iris; on the ciliary body and trabecular meshwork into the retina.…”

Section: Discussionmentioning

confidence: 99%

“…Klinische Anzeichen können, wie auch in dem hier beschriebenen Fall, der Nachweis einer retrokornealen Membran, schmerzhafte Hornhautdekompensation, Sekundärglaukom mit Verlegung des Kammerwinkels, Pupillarblock, traktive Netzhautablösung und letztendlich der Verlust des Sehvermögens sein. Aufgrund dessen ist die flächenhafte Epithelinvasion wie ein maligner Prozess zu bewerten und zu behandeln 3 . Ursache hierfür ist eine fortschreitende ein- bis mehrschichtige Ausbreitung schnell proliferierender Epithelzellen auf der Rückfläche der Hornhaut, über die Iris, den Ziliarkörper, das Trabekelmaschenwerk bis hin zur Retina.…”

Section: Diskussionunclassified

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Posttraumatic Ocular Hypotony Through Epithelial Downgrowth

Heinzelmann

Schober

Huth

et al. 2021

Klin Monbl Augenheilkd

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Background Intraocular epithelial downgrowth is a rare but potentially devastating posttraumatic complication. If left untreated, this may result in corneal decompensation, secondary angle-closure glaucoma, retinal detachment and blindness. Patient and Method A 10-year-old patient with penetrating globe injury and delayed wound management elsewhere presented with corneal melting and decompensation, retinal detachment and ocular hypotony. Following penetrating keratoplasty, cyclopexy and vitrectomy, corneal melting in the interface with renewed retinal detachment was noted within days. The hopeless prognosis required enucleation of the globe. Results Optical coherence tomography revealed not only corneal melting, but also markedly hyperreflective structures posterior to the cornea. Immunohistology demonstrated diffuse multi-layered nonkeratinised squamous cell epithelium on the posterior corneal surface, iris, ciliary bodies, and retina, as well as below the choroid, with renewed tractional retinal detachment. Conclusion Posttraumatic epithelial downgrowth may result in tractional retinal detachment, cyclodialysis cleft and/or corneal melting. Hyperreflective membrane deposits on OCT may be indicative of diffuse epithelial downgrowth. Especially in children, prompt wound closure in globe injuries is vital to avoid this serious posttraumatic complication.

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Section: Discussionmentioning

confidence: 99%

Section: Diskussionunclassified