Chirurgische Therapie der fulminanten Lungenembolie

Abstract

Surgical embolectomy for massive pulmonary embolism (PE) has become a rare procedure. Often, it is viewed as a last-chance option for patients undergoing cardiopulmonary resuscitation after massive PE. Thus thrombolytic therapy has become the treatment of choice. However, a significant proportion of patients suffers from residual obstruction after thrombolytic therapy and faces the development of chronic pulmonary hypertension. Therefore, some centers have regained interest in surgical embolectomy after improved risk stratification and reported very good results. Perioperative survival rates up to 89% have been reported. This was accomplished by surgery on the ECC-(extracorporeal circulation-)supported, beating, normothermic heart and utilization of special instruments. These encouraging results have been confirmed by the authors and others in patients with stable systemic hemodynamics but moderate to severe right ventricular dysfunction. The more widespread use of surgical embolectomy seems warranted. A randomized, controlled trial is overdue to determine the benefits of this therapy in stable patients compared with thrombolytic therapy if "best-practice" therapy is to be achieved for the patients' benefit.

Neue Aspekte zur Diagnostik und Therapie der akuten und chronischen pulmonalen Hypertonie

“…nach Operation, zur thrombolytischen Therapie vor, ist die chirurgische Thrombektomie ein erfolgversprechendes Verfahren, das, durch moderne Methoden unterstützt, zielgerichtet hervorragende Ergebnisse erzielt. Aleksic et al diskutieren aktuelle chirurgische Fragen [10].…”