“…In recent decades, there has been a significant rise in the use of various nanoparticles (NPs) in the food industry. These include lipid NPs as protective encapsulation systems of lipophobic nutrients, polysaccharide NPs-based films for food packaging, and inorganic NPs as food additives (Figure ). Alongside these exogenous NPs, endogenous food ingredients such as lipids, proteins, and carbohydrates, can also spontaneously assemble into various NPs during processing or gastrointestinal digestion. , Furthermore, due to the increasing plastic pollution in the environment, plastic NPs can easily be transferred from the environment to the human gastrointestinal tract through the food chain. , This highlights that the human intestinal system is constantly exposed to a variety of food-derived NPs.…”