Chitosan-based inks for 3D printing and bioprinting

Taghizadeh, Mohsen; Taghizadeh, Ali; Yazdi, Mohsen Khodadadi; Zarrintaj, Payam; Stadler, Florian J.; Ramsey, Joshua D.; Habibzadeh, Sajjad; Rad, Somayeh Hosseini; Naderi, Ghasem; Saeb, Mohammad Reza; Mozafari, Masoud; Schubert, Ulrich S.

doi:10.1039/d1gc01799c

Cited by 109 publications

(70 citation statements)

References 259 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Depending on the origin, polymers may exhibit many other desirable attributes, such as antibacterial, antioxidant, antioxidant, immunomodulatory, anti-inflammatory and antiviral properties. As a consequence, materials produced on this basis have a very wide range of applications [ 8 , 18 , 19 , 20 , 21 ].…”

Section: Introductionmentioning

confidence: 99%

The Functional and Application Possibilities of Starch/Chitosan Polymer Composites Modified by Graphene Oxide

Krystyjan

Khachatryan

et al. 2022

IJMS

View full text Add to dashboard Cite

This study describes functional properties of bionanocomposites consisting of starch/chitosan/graphene oxide (GO) obtained using the green synthesis method, such as water-barrier and optical properties, as well as the rate of degradation by enzymatic and acid hydrolysis. The toxicity of the composites and their effects on the development of pathogenic microflora during storage of meat food products was also investigated. Although the results showed that the barrier properties of the composites were weak, they were similar to those of biological systems. The studies carried out confirmed the good optical properties of the composites containing chitosan, which makes it possible to use them as active elements of packaging. The susceptibility of starch and chitosan films to enzymatic and acid hydrolyses indicates their relatively high biodegradability. The lack of toxicity and the high barrier against many microorganisms offer great potential for applications in the food industry.

show abstract

Section: Introductionmentioning

confidence: 99%

The Functional and Application Possibilities of Starch/Chitosan Polymer Composites Modified by Graphene Oxide

Krystyjan

Khachatryan

et al. 2022

IJMS

View full text Add to dashboard Cite

show abstract

“…It is also biodegradable and biocompatible, with low immunogenicity, and because of all these features, it has been widely studied for many biomedical applications, such as drug delivery [ 186 ] and wound healing [ 187 , 188 ]. The development of bioinks for 3D bioprinting is no exception, as very recently reviewed by Taghizadeh et al [ 44 ] in a work that thoroughly explores this topic, highlighting the reasons for the use of chitosan-based bioinks, the challenges and limitations of these materials, and their applications in the biomedical field. Chitosan-based bioinks have already been explored to fabricate 3D living structures laden with a panoply of cells for use in neural networks, bone, and skin tissue regeneration, among others [ 44 ].…”

Section: Polysaccharide-based Hydrogel Bioinksmentioning

confidence: 99%

“…The development of bioinks for 3D bioprinting is no exception, as very recently reviewed by Taghizadeh et al [ 44 ] in a work that thoroughly explores this topic, highlighting the reasons for the use of chitosan-based bioinks, the challenges and limitations of these materials, and their applications in the biomedical field. Chitosan-based bioinks have already been explored to fabricate 3D living structures laden with a panoply of cells for use in neural networks, bone, and skin tissue regeneration, among others [ 44 ]. Moreover, the emergence of commercially available chitosan-based bioinks (viz.…”

Section: Polysaccharide-based Hydrogel Bioinksmentioning

confidence: 99%

“…The developments in the field of bioinks for 3D bioprinting applications have been the theme of several appraisals [ 18 , 29 , 30 , 31 , 32 , 33 , 34 , 35 , 36 , 37 , 38 , 39 , 40 , 41 , 42 , 43 , 44 , 45 , 46 , 47 , 48 , 49 , 50 , 51 , 52 ]. Specifically, the progress over the last two decades was reviewed by Pedroza-Gonzalez et al [ 39 ], who provided a systematic analysis of more than 390 original papers from 2000 to 2019.…”

Section: Introductionmentioning

confidence: 99%

“…From a materials perspective, many of these revisions gave special emphasis to hydrogel bioinks [ 18 , 35 , 36 , 50 , 52 , 53 ] and to natural materials-based bioinks [ 33 , 38 ]. Moreover, recent reviews have also focused on the use of specific polysaccharides to produce bioinks, namely alginate [ 29 , 33 , 37 , 38 ], (nano)cellulose [ 32 , 35 , 40 , 41 , 46 , 47 , 49 ], chitosan [ 44 ], and hyaluronic acid [ 31 ]. Most recently, Mahendiran et al [ 37 ] provided an overview of 3D printing technologies and the use of different plant-based bioinks in tissue engineering, focusing on plant polysaccharides of terrestrial (starch, nanocellulose, and pectin) and marine (ulvan, sodium alginate (commonly referred as alginate), fucoidan, agarose, and carrageenan) origins [ 37 ].…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

A Guide to Polysaccharide-Based Hydrogel Bioinks for 3D Bioprinting Applications

Teixeira

Lameirinhas

Carvalho

et al. 2022

IJMS

View full text Add to dashboard Cite

Three-dimensional (3D) bioprinting is an innovative technology in the biomedical field, allowing the fabrication of living constructs through an approach of layer-by-layer deposition of cell-laden inks, the so-called bioinks. An ideal bioink should possess proper mechanical, rheological, chemical, and biological characteristics to ensure high cell viability and the production of tissue constructs with dimensional stability and shape fidelity. Among the several types of bioinks, hydrogels are extremely appealing as they have many similarities with the extracellular matrix, providing a highly hydrated environment for cell proliferation and tunability in terms of mechanical and rheological properties. Hydrogels derived from natural polymers, and polysaccharides, in particular, are an excellent platform to mimic the extracellular matrix, given their low cytotoxicity, high hydrophilicity, and diversity of structures. In fact, polysaccharide-based hydrogels are trendy materials for 3D bioprinting since they are abundant and combine adequate physicochemical and biomimetic features for the development of novel bioinks. Thus, this review portrays the most relevant advances in polysaccharide-based hydrogel bioinks for 3D bioprinting, focusing on the last five years, with emphasis on their properties, advantages, and limitations, considering polysaccharide families classified according to their source, namely from seaweed, higher plants, microbial, and animal (particularly crustaceans) origin.

show abstract

Bioinspired Hydrogels Through 3D Bioprinting

Niknam,

Rahmanian,

Mousavi

et al. 2023

Biomimicry Materials and Applications

View full text Add to dashboard Cite

Chitosan-based inks for 3D printing and bioprinting

Abstract: 3D printing gave biomedical engineering great potential to mimic native tissues, accelerated regenerative medicine, and enlarged capacity of drug delivery systems; thus, advanced biomimetic functional biomaterial developed by 3D-printing for tissue engineering demands.

Cited by 109 publications

References 259 publications

The Functional and Application Possibilities of Starch/Chitosan Polymer Composites Modified by Graphene Oxide

The Functional and Application Possibilities of Starch/Chitosan Polymer Composites Modified by Graphene Oxide

A Guide to Polysaccharide-Based Hydrogel Bioinks for 3D Bioprinting Applications

Bioinspired Hydrogels Through 3D Bioprinting

Contact Info

Product

Resources

About