Chitosan‐Coated Magnetic Nanoparticles with Low Chitosan Content Prepared in One‐Step

Osuna, Yolanda; Gregorio‐Jáuregui, Karla M.; Gaona-Lozano, Jose G.; Garza-Rodríguez, Iliana M. de la; Ilyna, Anna; Barriga-Castro, Enrique Díaz; Saade, Hened; López, Raúl G.

doi:10.1155/2012/327562

Cited by 63 publications

(41 citation statements)

References 33 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Figure 1 shows the [7]. The samples did not show additional peaks or phases suggesting that the modified MagNPs did not suffer any structural change [8,9]. 3 Journal of Nanomaterials C-N bonds from N(CH 2 ) 2 , respectively [13].…”

Section: Resultsmentioning

confidence: 98%

Synthesis of Poly(N-vinylcaprolactam)-Grafted Magnetite Nanocomposites for Magnetic Hyperthermia

Morfin-Gutierrez

Meléndez‐Ortiz²,

Puente-Urbina

et al. 2018

Journal of Nanomaterials

View full text Add to dashboard Cite

In this study, the synthesis, characterization, and application of poly(N-vinylcaprolactam)-grafted magnetite nanocomposites for magnetic hyperthermia are reported. Superparamagnetic magnetite nanoparticles (MagNPs) with sizes in the range of 10–16 nm were synthesized by the coprecipitation method and then functionalized with vinyltrimethoxysilane (VTMS). MagNPs-VTMS coated with poly(N-vinylcaprolactam) (PNVCL) were prepared by free radical polymerization. The obtained materials were characterized by X-ray diffraction (XRD), transmission electron microscopy (TEM), vibration sample magnetometry (VSM), and Fourier transform infrared spectroscopy (FT-IR). The heating ability was evaluated under a magnetic field using a solid state induction heating equipment at 10.2 kA/m and 362 kHz. The MagNPs-PNVCL nanocomposites showed a behavior close to superparamagnetic materials, which is appropriated for magnetic hyperthermia treatment; in concentrations of 8 mg/mL, they were able to heat up, increasing the temperature up to 42°C in a period of time lower than 10 minutes.

show abstract

Section: Resultsmentioning

confidence: 98%

Synthesis of Poly(N-vinylcaprolactam)-Grafted Magnetite Nanocomposites for Magnetic Hyperthermia

Morfin-Gutierrez

Meléndez‐Ortiz²,

Puente-Urbina

et al. 2018

Journal of Nanomaterials

View full text Add to dashboard Cite

show abstract

“…The preparation of chitosan modified magnetic nanoparticles is of great interest to researchers [ 10 , 11 ]. This polymer has been used successfully to colloidally stabilize metal oxide nanoparticles, and it has also been used as a matrix for enzyme immobilization through numerous amino groups, which interact with enzymes as shown in Figure 1 [ 6 ].…”

Section: Introductionmentioning

confidence: 99%

Development of Chitosan Functionalized Magnetic Nanoparticles with Bioactive Compounds

2020

View full text Add to dashboard Cite

In this study, magnetic maghemite nanoparticles, which belong to the group of metal oxides, were functionalized with chitosan, a non-toxic, hydrophilic, biocompatible, biodegradable biopolymer with anti-bacterial effects. This was done using different synthesis methods, and a comparison of the properties of the synthesized chitosan functionalized maghemite nanoparticles was conducted. Characterization was performed using scanning electron microscopy (SEM) and vibrating sample magnetometry (VSM). Characterizations of size distribution were performed using dynamic light scattering (DLS) measurements and laser granulometry. A chitosan functionalization layer was confirmed using potentiometric titration on variously synthesized chitosan functionalized maghemite nanoparticles, which is important for further immobilization of bioactive compounds. Furthermore, after activation of chitosan functionalized maghemite nanoparticles with glutaraldehyde (GA) or pentaethylenehexamine (PEHA), immobilization studies of enzyme cholesterol oxidase (ChOx) and horseradish peroxidase (HRP) were conducted. Factors influencing the immobilization of enzymes, such as type and concentration of activating reagent, mass ratio between carrier and enzyme, immobilization time and enzyme concentration, were investigated. Briefly, microparticles made using the chitosan suspension cross-linking process (MC2) proved to be the most suitable for obtaining the highest activity of immobilized enzyme, and nanoparticles functionalized with chitosan using the covalent binding method (MC3) could compete with MC2 for their applications.

show abstract

“…In addition, xylanase has been shown to covalently immobilize on chitosan (Manrich et al, 2010); alginate beads (Jampala et al, 2017); and magnetic nanoparticles (Soozanipour et al, 2015;Shahrestani et al, 2016). As support for enzyme immobilization, chitosan, a natural polymeric support, has previously been reported to have the ability to support cellulase and xylanase since it has various functional group, and is inexpensive, inert, hydrophilic and biocompatible (Osuna et al, 2012). Micro-sized and nanosized chitosan magnetic particles were used since their larger surface area will resolve the mass transfer resistance between the immobilized enzyme and the substrate.…”

Section: Introductionmentioning

confidence: 99%

Cellulase and Xylanase Immobilized on Chitosan Magnetic Particles for Application in Coconut Husk Hydrolysis

Hamzah¹,

Ainiyah²,

Ramadhani³

et al. 2019

IJTech

View full text Add to dashboard Cite

Cellulase and xylanase were covalently immobilized on chitosan magnetic particles. They were employed as catalysts to produce reducing sugar from coconut husk individually and simultaneously. Fourier Transform Infrared Spectroscopy (FT-IR) and Bradford's protein analysis confirmed that the enzymes were covalently immobilized on the support. Cellulase from Aspergillus niger and Trichoderma reesei immobilized on chitosan magnetic microparticles yielded 0.352 g/L and 0.316 g/L of reducing sugar respectively, while immobilized xylanase from Trichoderma longibachterium yielded 0.432 g/L. The simultaneous use of cellulase and xylanase produced 0.8034 g/L of sugar, and the addition of glutaraldehyde as a cross-linking agent increased the amount of reducing sugar. Enzyme could maintain its activity at 91% for up to five cycles. Using nanosized particles resulted in a sugar yield of 0.49 g/l and 54.7 % of its activity maintained after five cycles.

show abstract

Chitosan‐Coated Magnetic Nanoparticles with Low Chitosan Content Prepared in One‐Step

Cited by 63 publications

References 33 publications

Synthesis of Poly(N-vinylcaprolactam)-Grafted Magnetite Nanocomposites for Magnetic Hyperthermia

Synthesis of Poly(N-vinylcaprolactam)-Grafted Magnetite Nanocomposites for Magnetic Hyperthermia

Development of Chitosan Functionalized Magnetic Nanoparticles with Bioactive Compounds

Cellulase and Xylanase Immobilized on Chitosan Magnetic Particles for Application in Coconut Husk Hydrolysis

Contact Info

Product

Resources

About