Chitosan/collagen composite films as wound dressings encapsulating allantoin and lidocaine hydrochloride

Yaşayan, Gökçen; Karaca, Gizem; Akgüner, Zeynep Püren; Bal‐Öztürk, Ayça

doi:10.1080/00914037.2020.1740993

Cited by 53 publications

(39 citation statements)

References 65 publications

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“…Once the amoxicillin had been modified with activated ester groups, it was able to form covalent bonds with the NH 2 groups in the bacterial cellulose. The resulting bacterial cellulose composite demonstrated up to a 95% reduction in the viability of C. albicans, E. coli and S. aureus [ 127 ].…”

Section: Bacterial Cellulose Composites In Wound Dressingsmentioning

confidence: 99%

Recent Advances and Applications of Bacterial Cellulose in Biomedicine

et al. 2021

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Bacterial cellulose (BC) is an extracellular polymer produced by Komagateibacter xylinus, which has been shown to possess a multitude of properties, which makes it innately useful as a next-generation biopolymer. The structure of BC is comprised of glucose monomer units polymerised by cellulose synthase in β-1-4 glucan chains which form uniaxially orientated BC fibril bundles which measure 3–8 nm in diameter. BC is chemically identical to vegetal cellulose. However, when BC is compared with other natural or synthetic analogues, it shows a much higher performance in biomedical applications, potable treatment, nano-filters and functional applications. The main reason for this superiority is due to the high level of chemical purity, nano-fibrillar matrix and crystallinity. Upon using BC as a carrier or scaffold with other materials, unique and novel characteristics can be observed, which are all relatable to the features of BC. These properties, which include high tensile strength, high water holding capabilities and microfibrillar matrices, coupled with the overall physicochemical assets of bacterial cellulose makes it an ideal candidate for further scientific research into biopolymer development. This review thoroughly explores several areas in which BC is being investigated, ranging from biomedical applications to electronic applications, with a focus on the use as a next-generation wound dressing. The purpose of this review is to consolidate and discuss the most recent advancements in the applications of bacterial cellulose, primarily in biomedicine, but also in biotechnology.

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Section: Bacterial Cellulose Composites In Wound Dressingsmentioning

confidence: 99%

Recent Advances and Applications of Bacterial Cellulose in Biomedicine

et al. 2021

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“…The healing process of chronic wounds takes more than three months. Some examples include diabetic ulcers, decubitus ulcers, and arterial ulcers, significantly reducing patients’ life quality [ 16 ]. The wound-healing process is a complex cascade of cellular events composed of reconstitution, resurfacing, and the restoration of the normal form of damaged skin [ 17 ].…”

Section: Phases Of Wound Healing Processmentioning

confidence: 99%

Polymer-Based Scaffolds Loaded with Aloe vera Extract for the Treatment of Wounds

et al. 2021

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The treatment of wounds is one challenging biomedical field due to delayed wound healing common in chronic wounds. Several factors delay wound healing, including microbial infections, malnutrition, underlying physiological conditions, etc. Most of the currently used wound dressing materials suffer from poor antimicrobial properties, poor biodegradability and biocompatibility, and weak mechanical performance. Plant extracts, such as Aloe vera, have attracted significant attention in wound management because of their interesting biological properties. Aloe vera is composed of essential constituents beneficial for the wound healing process, such as amino acids, vitamins C and E, and zinc. Aloe vera influences numerous factors that are involved in wound healing and stimulates accelerated healing. This review reports the therapeutic outcomes of aloe vera extract-loaded polymer-based scaffolds in wound management.

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“…Skin wounds caused by trauma, burn, diabetes, genetic disorders, or surgery, resulting in great economic burden to healthcare system 2 . Particularly, aging population paired with an increase in the chronic disease such as diabetes and obesity, has led to an increase in the prevalence of chronic wounds 3,4 . In the United States, approximately 2% of population experience chronic wounds during their life‐times, represents over $25 billion in annual cost 5‐7 .…”

Section: Introductionmentioning

confidence: 99%

Advancements and future directions in the antibacterial wound dressings – A review

et al. 2020

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Wound repair is a complex process that has not been entirely understood. It can conclude in several irregularities. Hence, designing an appropriate wound dressing that can accelerate the healing period is critical. Infections, a major obstacle to wound repair, cause an elevated inflammatory responses and result in ultimate outcome of incomplete and prolonged wound repair. To overcome these shortcomings, there is a growing requirement for antibacterial wound dressings. Dressings with antibacterial activities and multifunctional behaviors are highly anticipated to avoid the wound infection for successful healing. The aim of this review is not only to concentrate on the importance of antibacterial dressings for wound healing applications but also to discuss recent studies and some future perspectives about antibacterial wound dressings.

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Chitosan/collagen composite films as wound dressings encapsulating allantoin and lidocaine hydrochloride

Cited by 53 publications

References 65 publications

Recent Advances and Applications of Bacterial Cellulose in Biomedicine

Recent Advances and Applications of Bacterial Cellulose in Biomedicine

Polymer-Based Scaffolds Loaded with Aloe vera Extract for the Treatment of Wounds

Advancements and future directions in the antibacterial wound dressings – A review

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