2024
DOI: 10.1080/17435889.2024.2359364
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Chitosan decorated oleosomes loaded propranolol hydrochloride hydrogel repurposed for Candida albicans -vaginal infection

Moaz A Eltabeeb,
Menna M Abdellatif,
Mohamed A El-Nabarawi
et al.

Abstract: Aim: Our investigation aims to estimate the antifungal effect of propranolol hydrochloride (PNL). Methods: Oleosomes (OLs) were fabricated by thin-film hydration and evaluated for entrapment efficiency (EE%), particle size (PS), polydispersity index (PDI), zeta potential (ZP), and amount of drug released after 6 h Q6h (%). Results: The optimal OL showed a rounded shape with optimum characteristics. The ex-vivo permeation and confoc… Show more

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