Chitosan Derivatives and Grafted Adjuncts with Unique Properties

Merzendorfer, Hans

doi:10.1007/978-3-030-12919-4_3

Cited by 7 publications

(2 citation statements)

References 522 publications

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“…The presence of primary amines at the C-2 position of the d-glucosamine and hydroxyl groups gives to chitosan unique structural features, that allow specific chemical reactions to provide water soluble chitosan derivatives under neutral/alkaline pH, and to attach new functional groups for specific applications. In this respect, the acylation, alkylation, carboxyalkylation, quaternization, thiolation, sulfation, phosphorylation, attachment of carbohydrates and dendrimers, and graft copolymerization are chemical reactions applied with good and proven results for chitosan modification [130].…”

Section: Chitosan and Chitosan Derivativesmentioning

confidence: 99%

Review on Polysaccharides Used in Coatings for Food Packaging Papers

2020

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Paper and board show many advantages as packaging materials, but the current technologies employed to obtain adequate barrier properties for food packaging use synthetic polymers coating and lamination with plastic or aluminium foils—treatments which have a negative impact on packaging sustainability, poor recyclability and lack of biodegradability. Recently, biopolymers have attracted increased attention as paper coatings, which can provide new combinations in composite formulas to meet the requirements of food packaging. The number of studies on biopolymers for developing barrier properties of packaging materials is increasing, but only a few of them are addressed to food packaging paper. Polysaccharides are viewed as the main candidates to substitute oil-based polymers in food paper coating, due to their film forming ability, good affinity for paper substrate, appropriate barrier to gases and aroma, and positive effect on mechanical strength. Additionally, these biopolymers are biodegradable, non-toxic and act as a matrix for incorporation additives with specific functionalities for coated paper (i.e., active-antimicrobial properties). This paper presents an overview on the availability and application of polysaccharides from vegetal and marine biomass in coatings for foods packaging paper. The extraction methods, chemical modification and combination routes of these biopolymers in coatings for paper packaging are discussed.

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Section: Chitosan and Chitosan Derivativesmentioning

confidence: 99%

Review on Polysaccharides Used in Coatings for Food Packaging Papers

2020

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“…HA participates in some cell signal transduction through hyaluronan-binding proteins, thereby regulating cell attachment and supporting cell migration [19]. HA can be degraded by hyaluronidase, and the degradation products flow into the liver through the blood and are catabolized [20]. The excellent biocompatibility and biodegradability of HA have attracted much attention in the fields of regenerative medicine and tissue engineering.…”

Section: Introductionmentioning

confidence: 99%

In Vitro Evaluation of a Composite Gelatin–Hyaluronic Acid–Alginate Porous Scaffold with Different Pore Distributions for Cartilage Regeneration

Haung

Lin

Liu

et al. 2021

Gels

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Although considerable achievements have been made in the field of regenerative medicine, since self-repair is not an advanced ability of articular cartilage, the regeneration of osteochondral defects is still a challenging problem in musculoskeletal diseases. Cartilage regeneration aims to design a scaffold with appropriate pore structure and biological and mechanical properties for the growth of chondrocytes. In this study, porous scaffolds made of gelatin, hyaluronic acid, alginate, and sucrose in different proportions of 2 g (SL2) and 4 g (SL4) were used as porogens in a leaching process. Sucrose with particle size ranges of 88–177 μm (Hμ) and 44–74 μm (SHμ) was added to the colloid, and the individually cross-linked hydrogel scaffolds with controllable pore size for chondrocyte culture were named Hμ-SL2, Hμ-SL4, SHμ-SL2 and SHμ-SL4. The perforation, porosity, mechanical strength, biocompatibility, and proliferation characteristics of the hydrogel scaffold and its influence on chondrocyte differentiation are discussed. Results show that the addition of porogen increases the porosity of the hydrogel scaffold. Conversely, when porogens with the same particle size are added, the pore size decreases as the amount of porogen increases. The perforation effect of the hydrogel scaffolds formed by the porogen is better at 88–177 μm compared with that at 44–74 μm. Cytotoxicity analysis showed that all the prepared hydrogel scaffolds were non-cytotoxic, indicating that no cross-linking agent residues that could cause cytotoxicity were found. In the proliferation and differentiation of the chondrocytes, the SHμ-SL4 hydrogel scaffold with the highest porosity and strength did not achieve the best performance. However, due to the compromise between perforation pores, pore sizes, and strength, as well as considering cell proliferation and differentiation, Hμ–SL4 scaffold provided a more suitable environment for the chondrocytes than other groups; therefore, it can provide the best chondrocyte growth environment for this study. The development of hydrogels with customized pore properties for defective cartilage is expected to meet the requirements of the ultimate clinical application.

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Nanotoxicity and Environmental Risks of Magnetic Iron Oxide Nanoparticles and Nanohybrids

Leonel

Mansur

2022

Handbook of Magnetic Hybrid Nanoalloys and Their Nanocomposites

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Chitosan Derivatives and Grafted Adjuncts with Unique Properties

Cited by 7 publications

References 522 publications

Review on Polysaccharides Used in Coatings for Food Packaging Papers

Review on Polysaccharides Used in Coatings for Food Packaging Papers

In Vitro Evaluation of a Composite Gelatin–Hyaluronic Acid–Alginate Porous Scaffold with Different Pore Distributions for Cartilage Regeneration

Nanotoxicity and Environmental Risks of Magnetic Iron Oxide Nanoparticles and Nanohybrids

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