Chitosan Fibers Modified with HAp/β–TCP Nanoparticles

Wawro, Dariusz; Pighinelli, Luciano

doi:10.3390/ijms12117286

Cited by 22 publications

(13 citation statements)

References 23 publications

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“…This calcium phosphate is easily identified by presenting a broad band in 900-1200 cm -1 ; observed the presence of the peak at 724 cm -1 , characteristic of the symmetric mode (P-O-P) assigned to distortion of P-O. Since the peak at 1211 cm -1 is characteristic of a non-degenerate deformation of hydrogen groups -OPO 3 , -H, O-PO 3 , common ions HPO 4 -2 , the presence of this group may be a consequence of the interaction of water molecules in the structure [18][19][20][21] (Figure 2). …”

Section: Resultsmentioning

confidence: 96%

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Properties of Hydrochloric Chitosan Solutions Modified With Nano- Calcium Phosphate Complex.

Pighinelli¹,

Mf²,

Rl³

2015

J Tissue Sci Eng

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Nature itself uses materials like cellulose to provide the structure of plants, chitin as the exoskeleton of several insects and molluscs, collagen for mechanical support in connective tissues and so on. At present, the socioeconomic situation of the modern world has raised the interest in renewable materials to use in regenerative medicine. The composition of Chitosan and/or Calcium Phosphates are derived from the junction of two or more different materials, containing organic and inorganic materials, including characteristics of both materials like bioactivity and biodegradability and biocompatibility with human tissues.The chemical characteristics of chitosan and nano B-TCP / HAp complex showed that both of the components organic and inorganic exist in the material showing a good stability of the nano-ceramic formation in the chitosan salt solutions. All complex by Zeta-Potential, showing also a new method of preparations nanoparticles of calcium phosphates in chitosan solution from commercial calcium phosphates in micro size. These materials can be used in future for medical applications as a base for scaffolds production and as implants in regenerative medicine.

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Section: Resultsmentioning

confidence: 96%

“…Chitosan/ß-TCP/HAp complex solution was prepared according to a method elaborated in the Institute of Biopolymers and Chemical Fibers, Poland [17,18].…”

Section: Preparation Of Hydrochloric Chitosan/ ß-Tcp and Hap Complex mentioning

confidence: 99%

Properties of Hydrochloric Chitosan Solutions Modified With Nano- Calcium Phosphate Complex.

Pighinelli¹,

Mf²,

Rl³

2015

J Tissue Sci Eng

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“…Grain size fits mainly in the range 1.0 -10.0 μm, average particle size of HAp is 3.24 ± 0.81 µm, also according with the literature [15] …”

Section: Analysis Of the Particles Size Of The Hydroxyapatitementioning

confidence: 92%

“…The SEM analysis showed a HAp great ability to agglomeration and cluster formation, the small particles tend to agglomerate due to the increased intensity of the attractive forces on the repulsive, because the charge distribution on the surfaces and the water adsorption [15] [19] [25]. Samples 10 and 11 were chosen for further studies because shown the best structure and the highest content of calcium phosphates of the set of samples according with Table 1.…”

Section: Sem Study Of the Filmsmentioning

confidence: 99%

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Properties and Structure of Microcrystalline Chitosan and Hydroxyapatite Composites

Pighinelli¹,

Kucharska²

2014

JBNB

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The skeletal system in the human body is very important, provides support and gives shape to the body and provides a network between all soft tissues. The most common problems in hard tissues are bone fractures, defects or diseases which needed to be treated. The developments in artificial bone area seem to solve most of the hard tissue problems, on the other hand artificial bones themselves may cause other problems and in many cases they do not have sufficient mechanical properties and/or good biocompatibility. The importance of chitosan and its derivatives like microcrystalline chitosan has grown significantly over the last two decades due to its renewable and biodegradable source, and also because of the increase in the knowledge of its functionality in the technological and biomedical applications. The excellent biocompability, biofunctionality, and non-antigenic property make the chitosan and its derivatives as a microcrystalline chitosan an ideal material for tissue regeneration. To improve the suitability of chitosan for bone tissue engineering, the composites of MCCh and hydroxyapatite were studied. In the present work the characterization of the MCCh and composites with HAp in form of films and sponges, is based on physico-chemical tests, morphology, structure, particle size of HAp powder and distribution in the polymer matrix. The compositions with film and sponge shape are derived from the junction of two different materials, containing organic and inorganic substances. All sponge preparations, with HAp/MCCh have a well-shaped 3-dimensional structure, which could be used as implants in orthopedic surgery for a scaffolds base for medical applications.

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