Chitosan in Dentistry

Releasing growth factors from activated human platelets after chitosan stimulation: a possible bio‐material for platelet‐rich plasma preparation

“…Clot formation has been proposed to be one aspect of enhanced wound healing of chitosan based on the findings of a better neo‐endothelial healing and a thin clot layer completely covering the implanted chitosan‐impregnated vascular prostheses (Van der Lei & Wildevuur 1989; Van der Lei et al 1991). Regarding oral specialties, chitosan has been used in the surgical procedures of periodontitis, apicoectomy, tooth‐extraction and palatal wounds (Sapelli et al 1986; Muzzarelli et al 1989, 1993). Excellent periodontal regeneration has been reported after the implantation of chitosan in the one‐wall alveolar bony defect in dogs (Park et al 2003).…”

Chitin derivatives. I. Kinetics of the heat-induced conversion of chitosan to chitin

“…3 ) . The tan &transitions occur after shorter time periods when heated at 140°C as compared to 100°C; and the storage modulus rises Figure 3 Isothermal cure profiles of chitosonium acetate (ChAc) at two temperatures, 100°C and 14OoC. The storage modulus shows a progressive increase with time, and the tan 6 shows two overlapping transitions.…”

Eight‐week histological analysis on the effect of chitosan on surgically created one‐wall intrabony defects in beagle dogs

“…Recent reports have noted the efficacy of chitosan in promoting oral wound healing in human studies. In 1986, Sapelli et al reported a positive outcome after applying chitosan powder to periodontal pockets, palatal wounds, and extraction sockets (Sapelli et al 1986). Muzzarelli et al (1989) observed a decrease in fibroplasia and the promotion of tissue organization after using a chitosan gel.…”