Chitosan Nanoparticles Prepared From Lucilia Cuprina Maggots as Antibacterial Agent

Hassan, Mostafa I.; Taher, Fatma A.; Mohamed, Aly F.; Kamel, Mohammad R

doi:10.21608/jesp.2016.88251

Cited by 4 publications

(2 citation statements)

References 7 publications

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“…In an alternative report, the Lucilia cuprina larvae shield was identified as a promising source of chitin. The chitosan nanoparticles produced from it displayed a DDA value 80.5% and more antibiotic activity toward Bacillus subtilis and Klebsiella pneumonia . Recently, it was found that microbe-originated chitosan has attracted increased acceptance because of its advantage in producing unvarying and untainted products with accurate features.…”

Section: Sources and Properties Of Chitosanmentioning

confidence: 99%

“…The chitosan nanoparticles produced from it displayed a DDA value 80.5% and more antibiotic activity toward Bacillus subtilis and Klebsiella pneumonia. 44 Recently, it was found that microbeoriginated chitosan has attracted increased acceptance because of its advantage in producing unvarying and untainted products with accurate features. Furthermore, marine chitosan is limited due to different seasonal and environmental dissimilarities, elucidating the budding mandate for a microbial source.…”

Section: Sources and Properties Of Chitosanmentioning

confidence: 99%

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Chitosan Derivatives as Carriers for Drug Delivery and Biomedical Applications

Manna

Seth

Gupta

et al. 2023

ACS Biomater. Sci. Eng.

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Over the past few decades, chitosan (CS) has gained the attention of researchers investigating newer biomaterial-based carriers for drugs in pharmaceutical and biomedical research. Combined with its nontoxic behavior, biodegradability, and biocompatibility, chitosan has found widespread applications in the fields of drug delivery, tissue engineering, and cosmetics. As a novel drug carrier, chitosan is regarded as one of the promising biomaterials in the pharmaceutical industry. The extensive use of this cationic biopolysaccharide in the delivery of therapeutic agents has brought a few limitations of chitosan into the limelight. Various chemical modifications of chitosan can minimize these limitations and improve the efficacy of chitosan as a drug carrier. The effectiveness of several chemically modified chitosan derivatives, including trimethyl chitosan, thiolated chitosan, PEGylated chitosan, and other chitosan derivatives, has been investigated by many researchers for the controlled and target specific delivery of therapeutics. The chemically modified chitosan derivatives exhibited greater importance in the current scenario on drug delivery due to their solubility in wide range of media along with their interaction with pharmaceutically active ingredients. Chitosan derivatives have also attracted attention in several biomedical fields, including wound healing, hyperthermia therapy, tissue engineering, and bioadhesives. The present review narrates the sources and common physicochemical properties of chitosan, including several important synthetic modifications to obtain chemically modified chitosans and their applications in targetspecific drug delivery, along with several biomedical applications.

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Section: Sources and Properties Of Chitosanmentioning

confidence: 99%

Section: Sources and Properties Of Chitosanmentioning

confidence: 99%

Chitosan Derivatives as Carriers for Drug Delivery and Biomedical Applications

Manna

Seth

Gupta

et al. 2023

ACS Biomater. Sci. Eng.

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Studying the Effect of Chitosan on Bacillus Cereus Producing Cereulide Toxin in Milk and Some Dairy Desserts

El-Nisr¹,

Elsherif²,

Hendy³

et al. 2021

J microb biotech food sci

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A total of 150 samples of raw milk and two types of refrigerated processed dairy desserts dishes (cooked rice with milk and Mehalabia dishes) (50 for each) were collected from dairy shops and local restaurants in Assuit City, Egypt. ISO7932 method was used for enumeration of B. cereus, afterwards a PCR was performed to confirm the presence of cereulide toxin (ces) gene. In addition, the effect of different concentrations of chitosan and chitosan nanoparticles (CNPs) (0.05, 1%) on B. cereus was studied in pasteurized milk.The shelf life was evaluated by clot on boiling test and Ph value. Their pathological effect was detected by orally administration to experimental rats to investigate their adverse effect on rats liver and intestine using histopathological examination. The most prominent potent bactericidal effect was observed inCNPs 1%, B. cereus count reached to undetectable level at 5th day of refrigerated storage. The pasteurized milk inoculated with B. cereus, chitosan and CNPs showed some pathological lesions in rats treated with B. cereus,while the chitosan 0.5% had antibacterial activities without cytotoxic effect on rat tissues, alternatively to CNPs 1%, which exist edematous tips of intestinal villi and mild kupffer cells activation in liver.Therefore, our results contribute data that are primary to indicate the risk of food poisoning due to B. cereus and trials to control that in food by careful using of nanotechnology. However, the additional researches are needed to safe using of this technology even on natural nano-materials as it at nano-size gain new qualities.

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Preparation, Characterization and Anticancer Activity of Chitosan Prepared from the American Cockroach, Periplaneta americana

Mahboub

Hassan

Bream

et al. 2021

Egyptian Academic Journal of Biological Sciences. A, Entomology

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in 1% acetic acid and Fourier transform infrared spectroscopy (FT-IR) analysis. The cytotoxicity of chitosan was investigated against Hepatoblastoma (HepG2) and Breast cancer (MCF7) cell lines by the MTT assay. The cytotoxicity has a positive relationship with the chitosan concentration. The half-maximal growth inhibitory concentrations (IC50) were 329 and 195 µg/ml with HepG2 and MCF7, respectively. Therefore, Chitosan may be a potential natural compound for the treatment of human hepatoblastoma (HepG2) and breast cancer (MCF7).

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Chitosan Nanoparticles Prepared From Lucilia Cuprina Maggots as Antibacterial Agent

Cited by 4 publications

References 7 publications

Chitosan Derivatives as Carriers for Drug Delivery and Biomedical Applications

Chitosan Derivatives as Carriers for Drug Delivery and Biomedical Applications

Studying the Effect of Chitosan on Bacillus Cereus Producing Cereulide Toxin in Milk and Some Dairy Desserts

Preparation, Characterization and Anticancer Activity of Chitosan Prepared from the American Cockroach, Periplaneta americana

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