Chitosan, the Marine Functional Food, Is a Potent Adsorbent of Humic Acid

Abstract

Chitosan is prepared by the deacetylation of chitin, the second-most abundant biopolymer in nature, and has applicability in the removal of dyes, heavy metals and radioactive waste for pollution control. In weight-reduction remedies, chitosan is used to form hydrogels with lipids and to depress the intestinal absorption of lipids. In this study, an experimental method was implemented to simulate the effect of chitosan on the adsorption of humic acid in the gastrointestinal tract. The adsorption capacity of chitosan was measured by its adsorption isotherm and analyzed using the Langmuir equation. The results showed that 3.3 grams of humic acid was absorbed by 1 gram of chitosan. The adsorption capacity of chitosan was much greater than that of chitin, diethylaminoethyl-cellulose or activated charcoal. Cellulose and carboxymethyl-cellulose, a cellulose derivative with a negative charge, could not adsorb humic acid in the gastrointestinal tract. This result suggests that chitosan entraps humic acid because of its positive charge.

Effects of adding resorbable chitosan microspheres to calcium phosphate cements for bone regeneration

“…In addition, the surface of CTS is hydrophilic, and this is conducive for cells to adhere, proliferate and differentiate [16]. Because of these properties chitosan has been recently used to improve currently used CPCs [17][18][19]. However, previous studies have mainly focused on adding chitosan to liquid components of CPCs or preparing chitosan fibers for CPC scaffolds [20,21].…”

Supplementation of Chitosan Alleviates High-Fat Diet-Enhanced Lipogenesis in Rats via Adenosine Monophosphate (AMP)-Activated Protein Kinase Activation and Inhibition of Lipogenesis-Associated Genes

“…8 Chitosan is also recognized as a marine functional food that it is shown to exhibit antidiabetic and antiobesity activity due to the indigestible characteristic acting as dietary fiber. 9,10 Several studies have shown that chitosan can reduce liver cholesterol by decreasing cholesterol absorption and increasing fecal fat excretion in human and animals, which may contribute to weight loss. 11,12 Our previous study has also found that longterm chitosan feeding in a type 2 diabetic rat model suppresses plasma adipocytokines and lipid accumulation in livers and adipose tissues, which may further reduce insulin resistance in diabetic rats.…”

Chitosan adsorbents for dye removal: a review

“…) and applications in many fields (biotechnology, medicine, membranes, cosmetics, food industry etc. ), but also because of its adsorption potential.…”