1990
DOI: 10.1177/014107689008300108
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Chlamydia Trachomatis and Inflammatory Bowel Disease - a Coincidence?

Abstract: Serological tests of 35 patients suffering from inflammatory bowel disease were compared to those of 35 healthy controls. The tests were performed using the indirect immunoperoxidase assay. Ninety-three per cent of 15 patients with Crohn's disease had IgG antibodies against Chlamydia, compared to 26% in the control group. In the 20 patients with ulcerative colitis, 45% had IgG antibodies against Chlamydia, compared to 10% in the control group. High serum titres of IgG antibodies were found in most of the patie… Show more

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Cited by 16 publications
(9 citation statements)
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“…However, there is no clear association of C . trachomatis (non-LGV serovars) with GI pathology in humans [63, 64], which is similar to C . muridarum colonization in the mouse GI tract.…”
Section: Discussionmentioning
confidence: 99%
“…However, there is no clear association of C . trachomatis (non-LGV serovars) with GI pathology in humans [63, 64], which is similar to C . muridarum colonization in the mouse GI tract.…”
Section: Discussionmentioning
confidence: 99%
“…However, the suggestion thatC. irachomatis may play a role in the pathogenesis ofCrohn's disease has recently been resurrected [26]. Consequently, il was oi' interest ihat proliferative responses to this organism, hoth in patients wilh IBD and controls, were indeed low, providing evidenee against the involvement of C trachomatis in Ihe pathogenesis of IBD.…”
Section: Discussionmentioning
confidence: 99%
“…Differential diagnosis is by stool or blood culture or serology, as biopsies can show focal active colitis reminiscent of CD [13][14][15][16][17][18][19][20][21][22] . Other infectious microorganisms, which can cause diagnostic confusion, are Escherichia coli (E. coli) serotype O157:H7 [23] , Chlamydia trachomatis [24] , Mycobacterium tuberculosis [25] , Actinomyces spp [26] , Entamoeba histolytica [27] , Giardia lamblia [28] , Blastocystis hominis, Cryptococcus neoformans and Histoplasma capsulatum.…”
Section: Clinicopathological Evidencementioning
confidence: 99%