Chlamydial infection in homosexual men. Frequency of isolation of Chlamydia trachomatis from the urethra, ano-rectum, and pharynx.

McMillan, A; Sommerville, R. G.; McKIE, P. M. K.

doi:10.1136/sti.57.1.47

Cited by 25 publications

(17 citation statements)

References 11 publications

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“…Several studies have shown that the chlamydial isolation rate from the urethras of homosexual men is less than that from heterosexual men,78 and that rectal infection associated with C trachomatis is less common than urethritis caused by C trachomatis. [1][2][3] McMillan et al suggested that pharyngeal and rectal mucosa are less well suited than genital sites' to colonisation by chlamydiae.' Though the numbers of isolates obtained in our study were too small for us to draw any firm conclusions, we believe that direct immunofluorescence is an acceptable alternative technique to culture and that the IDEIA test is unsuitable for non-genital sites.…”

Section: Discussionmentioning

confidence: 99%

Prevalence of Chlamydia trachomatis infection in homosexual men.

Sulaiman¹,

Foster²,

Pugh³

1987

Sexually Transmitted Infections

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SUMMARY Chlamydial cell culture isolation rates from 51 unselected homosexual men were 9.3% from the urethra, 4-3% (pharynx), and 6.5% (rectum). All the positive cultures showed extremely few inclusions. Direct-mmunofluorescence with the Microtrak reagent (Syva) was an acceptable alternative technique for non-genital sites, whereas the infectious disease enzyme immunoassay (IDEIA) (Boots-Celltech) was unsuitable.

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Section: Discussionmentioning

confidence: 99%

Prevalence of Chlamydia trachomatis infection in homosexual men.

Sulaiman¹,

Foster²,

Pugh³

1987

Sexually Transmitted Infections

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“…Furthermore, micro-organisms known to be pathogenic or suspected of pathogenicity in the male urethra may be transmitted to the rectum and it is possible that some cause proctitis. Chlamydia trachomatis which appears to cause 50% of cases of non-gonococcal urethritis (NGU) has been isolated sporadically from the rectum (Darougar et al, 1972;Goldmeier and Darougar, 1977;McMillan, Sommerville and McKie, 1981) but its association with NGP is unknown. Ureaplasma urealyticum may cause a proportion of cases of NGU and can be isolated from the anal canal of females without difficulty (Munday, Furr and Taylor-Robinson, 1981) but there are no reports of the micro-organism having been isolated from the rectum of male homosexuals.…”

Section: Discussionmentioning

confidence: 99%

A microbiological study of non-gonococcal proctitis in passive male homosexuals

Munday

Johnson

Thomas

et al. 1981

Postgraduate Medical Journal

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Summary In a study of 180 male homosexual patients attending a venereal disease clinic, a correlation was sought between symptoms and signs of proctitis and the isolation of Neisseria gonorrhoeae, group B streptococci, Chlamydia trachomatis, Ureaplasma urealyticum, Mycoplasma hominis and herpes simplex virus. Faecal specimens were examined for enteric pathogens and serological tests for hepatitis B virus, syphilitic and chlamydial infections were performed. There was no association between proctitis, as diagnosed by examination of a Gram-stained rectal smear, and the isolation of any micro-organism or detection of a positive serological test. There was, in addition, no association between any symptom or abnormal physical sign and any positive microbiological findings. Since 23% of patients from whom N. gonorrhoeae was isolated had no abnormal physical signs, it is difficult to assign a pathogenic role to other micro-organisms isolated from patients with and without clinical signs of proctitis. Approaches to further investigation of the problem are discussed.

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“…[2][3][4][5] Quinn et al isolated chlamydiae from 14 (8%) of 171 homosexual men and described a wide range of conditions from severe ulcerative proctitis to asymptomatic infection. 2 The evidence presented suggested that severe disease was produced by lymphogranuloma venereum (LGV) serovars of C trachomatis, whereas milder disease was produced by oculogenital serovars.…”

Section: Introductionmentioning

confidence: 99%