Chloramine T and related N-halogeno-N-metallo reagents

Mechanistic chemistry of oxidation of balsalazide with acidic chloramine-T and bromamine-T: A comparative spectrophotometric kinetic study

“…7 The diverse nature of the chemistry of these compounds is due to their ability to act as halonium cations, hypohalite species and N-anions, which act both as bases and nucleophiles. 7 These compounds contain * For correspondence positive halogen with +1 oxidation state which are mild oxidants. They interact with a wide range of functional groups, affecting a variety of molecular transformations.…”

“…They interact with a wide range of functional groups, affecting a variety of molecular transformations. Review articles by Campbell and Johnson, 7 Bremner, 8 Banerji et al, 9 Agarwal and Upadhyay, 10 Amresto et al, 11 Geethanjali, 12 Kolaveri et al 13 and, very recently Jagadeesh and Puttaswamy 14 comprehensively covered almost all the research work pertaining to the kinetic and mechanistic aspects of oxidation reactions of diverse group of substrates with organic N-haloamines. The prominent member of this class of compounds is sodium N-chloro-ptoluenesulfonamide, commonly known as chloramine-T (CAT; p-CH 3 C 6 H 4 SO 2 NClNa 3H 2 O).…”

“…7 In general, both CAT and BAT undergo two electron change in their reactions. 22 The oxidation potential of CAT and BAT-PTS redox potential is pH dependent and it decreases with increase in pH of the medium.…”

PdCl2 Catalyzed and Uncatalyzed N-Oxidation of Naratriptan with Alkaline Chloramine-T: Delineation of Reaction Mechanisms and Kinetic Modelings

“…Organic N-haloamines show diverse chemical behavior. Their versatile nature is due to their ability to act as source of halonium cations, hypohalite species and N-anions which act both as bases and nucleophiles [5]. As a result, these reagents react with a wide range of functional groups affecting an array of molecular transformations [6][7][8][9].…”

Kinetics and Mechanism of Ruthenium(iii) Catalyzed Oxidation of Secondary Alcohols by Bromamine-T in Hydrochloric Acid Solutions

“…The important chlorine compound of this class, chloramine-T (CAT), which is a by-product in the saccharin manufacture, is a well-known reagent for the determination of diverse substrates. [1] Mechanistic aspects of many of these reactions have been documented. [1,2] The bromine analogue, bromamine-T ( p-CH 3 C 6 H 4 SO 2 NBrNaÁ3H 2 O or BAT), which can be prepared by the bromination of CAT, is found to be a better oxidizing agent than CAT.…”