Chloramphenicol loaded polylactide melt electrospun scaffolds for biomedical applications

Topological Manipulation of Fully Biobased Poly(epoxy imine): From Thermoplastic Elastomers to Covalent Adaptable Networks and Permanently Cross-Linked Networks

“…On the other hand, traditional polymers have been challenged by the depletion of petroleum and the price fluctuation of crude oils . In response, tremendous efforts have been devoted to designing and fabricating biobased polymers from renewable resources. , Some biobased thermoplastics such as polylactide and microbial polyester have been commercially available, which have practical applications in biomedical devices, packaging, disposable goods, and electronic products. − Biobased thermosets such as epoxies and polyurethanes have also been reported with renewable resources, such as vegetable oils, , furan derivatives, , eugenol, , vanillin, , and lignin, as feedstocks. , Various dynamic covalent bonds have been designed and incorporated into biobased thermosets to develop malleable, recyclable, and multi-functional biobased CANs. − Despite this significant progress, biobased CANs and thermosets are still limited by either complex and lengthy fabrication routes or poor mechanical performance. For example, the biobased thermosets or CANs, such as those prepared from commercially available vegetable oils, are limited by the low T g , inferior mechanical strength and poor ductility. − Some renewable aromatic compounds derived from natural resources such as vanillin, syringaldehyde, and ferulic acid have been explored to prepare high-performance biobased epoxy thermosets or CANs. − However, the fabrication of these polymers usually involves the synthesis and purification of epoxy monomers via costly complex procedures with low purified yields, which makes them commercially uncompetitive. − Moreover, all the biobased thermoplastics, CANs, and thermosets are prepared from various renewable chemicals through various synthetic approaches, which enhances the difficulty in the industrial-scale production of these polymers because specific feedstocks and unique equipment and technology are required for each new biobased polymer.…”

Electrospun Antimicrobial Drug Delivery Systems and Hydrogels Used for Wound Dressings

“…The electrospinning apparatus is gaining momentum in commercialization. Among the widely adopted electrospinning techniques, melt electrospinning [ 86 ], wet electrospinning [ 87 ], coaxial electrospinning [ 85 ], and self-bundling electrospinning [ 88 ] are the most commonly utilized. Electrospinning can generate polymer nanofibers (with diameters ranging between 50 and 1000 nm) through techniques such as wet or hot melt electrospinning [ 86 , 87 ].…”

Electrospun Poly(lactide) Fibers as Carriers for Controlled Release of Biochanin A

“…The drug release mostly corresponds to Higuchi’s mathematical model of substance release. With a decrease in the diameter of the fibers and an increase in the drug content in the polymer, a higher percentage of drug release in the first rapid phase, as well as in drug release at a higher rate, is observed [ 24 ].…”