Chlorogenic, Caffeic, and Ferulic Acids and Their Derivatives in Foods

Ovalbumin-coated Fe3O4nanoparticles as a nanocarrier for chlorogenic acid to promote the anticancer efficacy on MDA-MB-231 cells

“…3 Chlorogenic acid or 5-O-caffeoylquinic acid (5-CQA) is one of the main CGA isomers abundantly found in various edible plants. 3 Despite its effectiveness and safety, the use of CGA is limited by its low stability and poor bioavailability. 3,4 In recent years, the encapsulation method has emerged as a promising delivery system and has been successfully applied to many bioactives to increase the stability, bioavailability, and bioactivity.…”

“…3 Despite its effectiveness and safety, the use of CGA is limited by its low stability and poor bioavailability. 3,4 In recent years, the encapsulation method has emerged as a promising delivery system and has been successfully applied to many bioactives to increase the stability, bioavailability, and bioactivity. 5 Yang et al reported the successful synthesis of 5-CQA on selenium NPs, showing an improved in vitro inhibitory effect on Ab40 aggregation and reactive oxygen species formation.…”

“…Chlorogenic acids (CGAs) are a group of polyphenolic components of various fruits and vegetables, especially abundant in yerba mate tea and coffee. 3 CGAs have a number of pharmacological properties, such as anticancer, antibacterial, antimicrobial, anti-inflammatory, antiviral, and antimutagenic activities. 3 Chlorogenic acid or 5- O -caffeoylquinic acid (5-CQA) is one of the main CGA isomers abundantly found in various edible plants.…”

“…3 CGAs have a number of pharmacological properties, such as anticancer, antibacterial, antimicrobial, anti-inflammatory, antiviral, and antimutagenic activities. 3 Chlorogenic acid or 5- O -caffeoylquinic acid (5-CQA) is one of the main CGA isomers abundantly found in various edible plants. 3 Despite its effectiveness and safety, the use of CGA is limited by its low stability and poor bioavailability.…”

Multispectroscopic and Computational Investigations on the Binding Mechanism of Dicaffeoylquinic Acids with Ovalbumin

“…Recent studies have also demonstrated that these isomers of diCQAs have antiproliferative potential against human hepatocellular carcinoma and oral carcinoma cells . However, the applications of CGAs are limited because of their low stability and poor bioavailability. , …”