Chloropalladation Triggering the Cascade Annulation to Construct Functionalized Saturatedγ-Lactones in Ionic Liquids

Regio- and Stereoselective Synthesis of 1,2-Dihaloalkenes Using In-Situ-Generated ICl, IBr, BrCl, I2, and Br2

“…15 For example, dihaloalkenes containing two different halogens could undergo cross-coupling reactions in a step-wise manner for the installment of two different molecular fragments. 7,[16][17][18][19][20][21][22][23][24][25][26][27] In this regard, significant efforts have been devoted to the construction of dihaloalkenes. However, the regio-and stereoselective, yet environmentally friendly synthesis of dihaloalkenes with a broad scope is still challenging.…”

N-Iodosuccinimide-Promoted Regioselective Arylsulfenylation of Imidazo[1,2-a]pyridines with Disulfides

“…[C 2 O 2 mim]BF 4 [17] )参考相应文献合成. 151.7, 147.0, 126.9, 125.8, 125.7, 124.5, 123.6, 121.3, 116.8, 112.4, 110.8, 106.3, 55.8, 13.9 (d,J＝6.8 Hz,1H), 7.62 (d,J＝9.0 Hz,1H), 7.34～7.27 (m, 1H), 7.17 (d,J＝8.4 Hz,2H), 6.86 (d,J＝8.0 Hz,3H), 2.58 (s, 3H); 13 C NMR (100 MHz, CDCl 3 ) δ: 151.4, 145. 9,134.4,131.6,129.2,129.1,126.6,122.5,121.8,116.3,106.1,13.8;IR (KBr) (d,J＝6.0 Hz,1H), 7.66～7.55 (m, 1H), 7.33～7.28 (m, 1H), 6.90 (ddd, J＝16.8, 12.4, 5.4 Hz, 5H), 2.59 (s, 3H); 13 C NMR (100 MHz, CDCl 3 ) δ: 161.5 (d,J＝245.9 Hz),151.5,146.9,130.5,127.8 (d,J＝7.7 Hz),126.1,124.1,117.0,116.4 (d,J＝22.4 Hz),112.7,107.7,13.9;IR (KBr) 153.5, 148.5, 138.2, 136.5, 135.3, 130.1, 126.2, 124.9, 115.3, 114.3, 108.4, 20.8, 20.3, 14.1;IR (KBr) ν: 3043, 2914, 1646, 1463…”

“…9,134.4,131.6,129.2,129.1,126.6,122.5,121.8,116.3,106.1,13.8;IR (KBr) (d,J＝6.0 Hz,1H), 7.66～7.55 (m, 1H), 7.33～7.28 (m, 1H), 6.90 (ddd, J＝16.8, 12.4, 5.4 Hz, 5H), 2.59 (s, 3H); 13 C NMR (100 MHz, CDCl 3 ) δ: 161.5 (d,J＝245.9 Hz),151.5,146.9,130.5,127.8 (d,J＝7.7 Hz),126.1,124.1,117.0,116.4 (d,J＝22.4 Hz),112.7,107.7,13.9;IR (KBr) 153.5, 148.5, 138.2, 136.5, 135.3, 130.1, 126.2, 124.9, 115.3, 114.3, 108.4, 20.8, 20.3, 14.1;IR (KBr) ν: 3043, 2914, 1646, 1463, 1416, 1266 2,137.1,135.8,132.2,129.9,125.9,123.5,115.5,115.0,107.1,21.2,20.8,13.9;IR (KBr) 7, 147.1, 130.7, 127.7, 126.8 125.0, 121.9, 116.4, 116.1, 112.6, 107.9, 16.7, 13.9;IR (KBr) ν: 3057, 3028, 2957<...>…”

“…2,5-二甲基-3-(4-甲苯硫基)咪唑并[1,2-a]吡啶(3e): 产率 83%. 1 H NMR (400 MHz, CDCl 3 ) δ: 8.00 (s, 1H), 7.62(d, J＝8.8 Hz, 1H), 7.17(d, J＝8.8 Hz, 1H), 7.03(d, J＝7.6 Hz, 2H), 6.88(d, J＝7.6 Hz, 2H), 2.59 (s, 3H), 2.…”