Chlorosulfuric Acid

Abstract

The article contains sections titled: 1. Introduction 2. Physical Properties 3. Chemical Properties 4. Production 5. Safety Precautions, Transportation 6. Uses and Economic Aspects 7. Toxicology and Occupational Hygiene

Influence of Catalyst Concentration on Activity and Selectivity in Selective Methane Oxidation with Platinum Compounds in Sulfuric Acid and Oleum

“…Such behavior is well-known for the closely related Shilov chemistry and industrially applied reactions such as the Wacker process for acetaldehyde production. ,− Accurate quantitative statements are currently impossible, since intrinsic activities of distinct species as well as their corresponding concentrations in solution under reaction conditions are unknown. Advanced spectroscopic techniques might result in further insights here, but systematic studies with varying Cl – ion concentrations are additionally hampered by the fact that chloride ions can undergo oxidative transformations under the reaction conditions given. , …”

Development of a Green and Sustainable Manufacturing Process for Gefapixant Citrate (MK-7264) Part 1: Introduction and Process Overview

“…Alternatively, sulfonyl chlorides have been made from aryl halides or diazoniums, but this typically involves the use of unstable intermediates, gaseous reagents, and transition-metal catalysts . Chlorosulfonic acid has proven to be a highly efficient reagent in sulfonylating electron-rich arenes . However, as was seen in the initial clinical supply route, the most common products of these reactions are not sulfonyl chlorides but sulfonic acids such as compound 8 , despite the use of excess chlorosulfonic acid (Scheme ).…”