Chlorpheniramine impairs spatial choice learning in telencephalon-ablated fish

Romaguera, Fernanda; Mattioli, Rosana

doi:10.4067/s0716-97602008000300010

Cited by 2 publications

(3 citation statements)

References 48 publications

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“…On the other hand, in rodent models, both social defeat and chronically social stressed rats showed impaired performance in T-maze suggesting the test is sensitive to stress and suitable for assessing cognitive functions ( Ferragud et al, 2010 ; Novick et al, 2013 ). In addition, the T-maze apparatus is also used in other teleost fish model including common carp ( Cyprinus carpio ; Garina et al, 2016 ), killifish ( Kryptolebias marmoratus ; Rossi and Wright, 1953 ), mangrove rivulus ( Kryptolebias marmoratus ; Chang et al, 2012 ), Port Jackson sharks ( Heterodontus portusjacksoni ; Byrnes et al, 2016 ), goldfish ( Romaguera and Mattioli, 2008 ; Facciolo et al, 2011 , 2012 ), grey bamboo shark ( Chiloscyllium griseum ; Schluessel and Bleckmann, 2012 ), ornate wrasses ( Thalassoma pavo ; Zizza et al, 2017 ), mosquitofish ( Vinogradov et al, 2021 ), Siamese fighting fish ( Betta splendens ; Craft et al, 2003 , 2007 ; Shapiro and Jensen, 2009 ), Girardinus falcatus ( Bisazza et al, 2001 ), guppy ( Miletto Petrazzini et al, 2017 ) for different purposes such as learning test, lateralization and decision-making study. T-maze is an apparatus with great flexibility for assessing cognitive functions and the performance is sensitive to stress exposure, thus, should be incorporated in future social stress study as one of the behavioural parameters.…”

Section: Behavioural Tests In Fish Modelsmentioning

confidence: 99%

Teleosts as behaviour test models for social stress

Lai,

Mohd Zahir,

Liew

et al. 2023

Front. Behav. Neurosci.

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Stress is an important aspect of our everyday life and exposure to it is an unavoidable occurrence. In humans, this can come in the form of social stress or physical stress from an injury. Studies in animal models have helped researchers to understand the body’s adaptive response to stress in human. Notably, the use of behavioural tests in animal models plays a pivotal role in understanding the neural, endocrine and behavioural changes induced by social stress. Under socially stressed conditions, behavioural parameters are often measured physiological and molecular parameters as changes in behaviour are direct responses to stress and are easily assessed by behavioural tests. Throughout the past few decades, the rodent model has been used as a well-established animal model for stress and behavioural changes. Recently, more attention has been drawn towards using fish as an animal model. Common fish models such as zebrafish, medaka, and African cichlids have the advantage of a higher rate of reproduction, easier handling techniques, sociability and most importantly, share evolutionary conserved genetic make-up, neural circuitry, neuropeptide molecular structure and function with mammalian species. In fact, some fish species exhibit a clear diurnal or seasonal rhythmicity in their stress response, similar to humans, as opposed to rodents. Various social stress models have been established in fish including but not limited to chronic social defeat stress, social stress avoidance, and social stress-related decision-making. The huge variety of behavioural patterns in teleost also aids in the study of more behavioural phenotypes than the mammalian species. In this review, we focus on the use of fish models as alternative models to study the effects of stress on different types of behaviours. Finally, fish behavioural tests against the typical mammalian model-based behavioural test are compared and discussed for their viability.

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Section: Behavioural Tests In Fish Modelsmentioning

confidence: 99%

Teleosts as behaviour test models for social stress

Lai,

Mohd Zahir,

Liew

et al. 2023

Front. Behav. Neurosci.

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“…Plus-maze versions of the place and response learning tasks-including the dual-solution task-have been employed to examine learning and memory in chickens (Brookshire et al, 1961), terrestrial toads (Daneri et al, 2011), horses (Parker et al, 2009), salamanders (Kundey et al, 2016), and turtles (López et al, 2000;Rodríguez et al, 2002; see Figure 4E). In addition to studies in terrestrial and amphibious animals, water plus-maze versions of the place and response learning tasks have been readily employed to study memory in a variety of aquatic animals, including sharks (Fuss et al, 2014a,b), freshwater stingrays (Schluessel and Bleckmann, 2005), cuttlefish (Alves et al, 2007), crayfish (Tierney and Andrews, 2013), and goldfish (Rodríguez et al, 1994(Rodríguez et al, , 2002Salas et al, 1996a,b;Romaguera and Mattioli, 2008;McAroe et al, 2016). Aside from examining normal learning and memory abilities, some studies have used lesion techniques to examine the neural substrates of place learning in these animals.…”

Section: The Place and Response Learning Plus-maze Tasks In Other Spementioning

confidence: 99%

“…Aside from examining normal learning and memory abilities, some studies have used lesion techniques to examine the neural substrates of place learning in these animals. Lesions delivered to certain areas of the telencephalon believed to be homologous to the mammalian hippocampus, produce deficits in place learning, but not response learning, in sharks (Fuss et al, 2014a,b), goldfish (Salas et al, 1996a,b;Rodríguez et al, 2002;Romaguera and Mattioli, 2008), and turtles (Rodríguez et al, 2002). These findings demonstrate a similar role for the hippocampal formation in performing place learning functions across different species, suggesting that the ontogeny of hippocampal spatial memory processing may have an early evolutionary origin.…”

Section: The Place and Response Learning Plus-maze Tasks In Other Spementioning

confidence: 99%

Place vs. Response Learning: History, Controversy, and Neurobiology

Goodman

2021

Front. Behav. Neurosci.

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The present article provides a historical review of the place and response learning plus-maze tasks with a focus on the behavioral and neurobiological findings. The article begins by reviewing the conflict between Edward C. Tolman’s cognitive view and Clark L. Hull’s stimulus-response (S-R) view of learning and how the place and response learning plus-maze tasks were designed to resolve this debate. Cognitive learning theorists predicted that place learning would be acquired faster than response learning, indicating the dominance of cognitive learning, whereas S-R learning theorists predicted that response learning would be acquired faster, indicating the dominance of S-R learning. Here, the evidence is reviewed demonstrating that either place or response learning may be dominant in a given learning situation and that the relative dominance of place and response learning depends on various parametric factors (i.e., amount of training, visual aspects of the learning environment, emotional arousal, et cetera). Next, the neurobiology underlying place and response learning is reviewed, providing strong evidence for the existence of multiple memory systems in the mammalian brain. Research has indicated that place learning is principally mediated by the hippocampus, whereas response learning is mediated by the dorsolateral striatum. Other brain regions implicated in place and response learning are also discussed in this section, including the dorsomedial striatum, amygdala, and medial prefrontal cortex. An exhaustive review of the neurotransmitter systems underlying place and response learning is subsequently provided, indicating important roles for glutamate, dopamine, acetylcholine, cannabinoids, and estrogen. Closing remarks are made emphasizing the historical importance of the place and response learning tasks in resolving problems in learning theory, as well as for examining the behavioral and neurobiological mechanisms of multiple memory systems. How the place and response learning tasks may be employed in the future for examining extinction, neural circuits of memory, and human psychopathology is also briefly considered.

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Chlorpheniramine impairs spatial choice learning in telencephalon-ablated fish

Cited by 2 publications

References 48 publications

Teleosts as behaviour test models for social stress

Teleosts as behaviour test models for social stress

Place vs. Response Learning: History, Controversy, and Neurobiology

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