Choanal Atresia, CHARGE Association, and Congenital Nasal Stenosis

Keller, Jeffrey L.; Kacker, Ashutosh

doi:10.1016/s0030-6665(05)70285-1

Cited by 88 publications

(64 citation statements)

References 18 publications

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“…The nasal cavity is specifically designed to prepare the air before it passes into the lungs. 11 It is believed that nasal breathing contributes to the development of the nasofacial complex and benefits overall health. 12 Mucociliary clearance (MCC) plays a pivotal role in defending the respiratory system from the nose and upper airways to the lower respiratory tract.…”

Section: Introductionmentioning

confidence: 99%

Effects of rapid maxillary expansion on nasal mucociliary clearance

Babacan

Doruk

Uysal

et al. 2015

The Angle Orthodontist

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Objective: To evaluate the changes in nasal mucociliary clearance in orthodontic patients after rapid maxillary expansion (RME) therapy. Materials and Methods: Forty-two children (25 boys and 17 girls) participated in this study. The RME group consisted of 21 patients (mean age, 13.8 years), who had undergone RME at the initiation of orthodontic treatment. The control group consisted of 21 subjects (mean age, 13.6 years), who were attending the department of orthodontics for active orthodontic treatment. The nasal mucociliary clearance was assessed by the saccharin test. Saccharin transit times (STTs) were measured for each treated subject before expansion (T1), after RME (T2), and after a 3-month retention period (T3). Records were obtained at the same time intervals for each group. Results: The STT decreased significantly in the RME group after expansion and retention (P , .05). A statistically significant difference was found when the STTs of the control and RME groups were compared after expansion and retention (P , .05). Conclusions: The STTs of young orthodontic patients with maxillary narrowness and without any history of nasal or systemic disease were within normal limits. However, RME increased the mucociliary clearance in patients who had maxillary narrowness, having positive effects on nasal physiology and increasing nasal cavity volume. (Angle Orthod. 2016;86:250-254.)

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Section: Introductionmentioning

confidence: 99%

Effects of rapid maxillary expansion on nasal mucociliary clearance

Babacan

Doruk

Uysal

et al. 2015

The Angle Orthodontist

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“…Diagnosis was confirmed by computerized tomography of facial sinuses in 56.25% (9) and by nasofibroscopy in 31.25% (5).…”

Section: Resultsmentioning

confidence: 97%

“…It shows an incidence of 1:5,000-8,000 of live newborns, among which females are more affected than males in a 2:1 ratio. Unilateral defects are more common than bilateral ones, while the right nostril is twice more affected than the left nostril 4,5 . Presumably, 90% of defects are of bony type, although recent literature shows that 70% of cases are mixed defects, that is, of bone-membranous type [1][2][3] .…”

Section: Introductionmentioning

confidence: 99%

“…Presumably, 90% of defects are of bony type, although recent literature shows that 70% of cases are mixed defects, that is, of bone-membranous type [1][2][3] . Association with other anomalies and syndromes ranges from 20 to 50%, with no genetic corroboration; the most common syndrome is CHARGE (coloboma, cardiovascular malformations, growth and mental retardation, urogenital and ear anomalies 1,4,5 ). There are several theories explaining choanal atresia: I -persistence of oral-pharyngeal membrane; II -failure of the physiological oral-nasal membrane rupture; III -mesodermic tissue adherence; IV -growth of palatal processes [1][2][3]6 .…”

Section: Introductionmentioning

confidence: 99%

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Atresia de coana: análise de 16 casos - a experiência do HRAC-USP de 2000 a 2004

Bergonse

Carneiro

Vassoler

2005

Rev. Bras. Otorrinolaringol.

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Choanal atresia is a rare disease and the incidence is 1: 5000-8000 newborns alive. It is more comom among female and usually is associated with others malformations. Study design: clinical retrospective. When unilateral its diagnose may be postpone because its symptoms are less life threating. But when bilateral children have important respiratory insuficency. This articles will report incidence and the expirience of HRAC-USP.

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“…Several theories such as persistence of the buccopharyngeal membranes, failure of the oronasal membrane to rupture either the nasobuccal membrane of Hochstetter or buccopharyngeal membrane of the foregut, incomplete resorption of nasopharyngeal mesoderm, or locally misdirected mesodermal flow have been proposed to explain the occurrence of CA, but none have been universally accepted. This process occurs between the 4th and 11th fetal week (Dunham & Miller, 1992;Keller & Kacker, 2000;Samadi et al, 2003). Since neonates are obligate nasal breathing, at birth bilateral choanal atresia can manifest with dyspnea, cyanosis, severe hypoxia, and suckling difficulties, whereas the unilateral form presents monolateral rhinorrhea.…”

Section: Choanal Atresiamentioning

confidence: 99%