`Cholesteatoma' of the Orbit

Parke, David W.; Font, Ramon L.; Boniuk, Milton; McCrary, John A.

doi:10.1001/archopht.1982.01030030614015

Cited by 53 publications

(17 citation statements)

References 12 publications

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“…In the frontal sinus, cholesterol granuloma may be caused by disturbance of air drainage by middle nose polyps [5]. Some other authors have also reported a possible traumatic event over the frontal region with hematoma formation and retention of blood coagulated in the frontal sinus [6][7][8]. Cholesterol granuloma of the orbit has been less frequently associated with a previous trauma [6].…”

Section: Discussionsupporting

confidence: 41%

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Cholesterol Granuloma of the Orbit. Report of Cases and Analysis of Controversial Treatment

Román-Romero

González-García

2011

J. Maxillofac. Oral Surg.

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Section: Discussionsupporting

confidence: 41%

“…Due to the absence of epithelial elements [8], cholesterol granuloma of the orbit rarely recur. Consequently, some authors [9] have argued that complete extirpation of the adjacent bone is not necessary.…”

Section: Discussionmentioning

confidence: 99%

Cholesterol Granuloma of the Orbit. Report of Cases and Analysis of Controversial Treatment

Román-Romero

González-García

2011

J. Maxillofac. Oral Surg.

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“…The relative frequency of periorbital trauma compared to the infrequency of cholesterol granuloma may suggest that trauma does not play a significant role (Parke et al, 1982;Loeffler & Kommerell, 1997;Selva et al, 2003).…”

Section: Discussionmentioning

confidence: 40%

Recurrent Orbital Cholesterol Granuloma

Ong

McNab

2008

Orbit

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“…That might indicate that the clefts were not fresh lesions. Parke et al proposed that cholesteatomas of the orbit should be divided into two groups: "cholesterol granulomas" and "epidermoid or true cholesteatomas" [4]. The first includes lesions that contain no epithelial elements, and the second includes lesions that contain epithelial elements.…”

Section: Discussionmentioning

confidence: 45%

Cholesterol Crystal Deposition in Basal Cell Carcinoma: An Investigation of 4 Cases

Okamura¹,

Konno²,

Kawaguchi³

et al. 2015

JCDSA

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Cholesterol crystals are a primary cause of cholesterol embolism if they appear in vessels. Various papers have reported the involvement of cholesterol crystal deposition in cutaneous diseases such as xanthoma. However, no cases of cholesterol crystal involvement in cutaneous cancer have been reported. We report four cases of basal cell carcinoma with cholesterol crystal deposition, and discuss the mechanism(s) of the condition. Disease duration, anatomical site, histopathological features, and serum lipid profiles were investigated. The median disease duration was 3.5 years, and the sites of the lesions were the scrotum (one patient) and the nose (three patients). Histopathologically, there was necrotized tissue around the clefts. In addition, we detected frequent apoptotic cells around the cholesterol clefts in two of the patients by using the terminal deoxynucleotidyl transferase dUTP nick-end labeling method. Serum lipid levels were slightly elevated in two of the patients. In conclusion, cholesterol crystal deposition in basal cell carcinoma was considered to relate to a long disease duration with a tumor in a region that was subject to external irritation. Histopathologically, apoptotic cells around the cholesterol clefts indicated that lipids from the tumor cell membranes were one of the causes of cholesterol crystal deposition.

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`Cholesteatoma' of the Orbit

Cited by 53 publications

References 12 publications

Cholesterol Granuloma of the Orbit. Report of Cases and Analysis of Controversial Treatment

Cholesterol Granuloma of the Orbit. Report of Cases and Analysis of Controversial Treatment

Recurrent Orbital Cholesterol Granuloma

Cholesterol Crystal Deposition in Basal Cell Carcinoma: An Investigation of 4 Cases

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