Cholesterol

Biochemical and Hematological Analysis after Exposure to Hazardous Materials during Shoe Making

“…Cholesterol is an essential structural component of mammalian cell membranes and an important component in the synthesis of steroid hormones, bile acids and several fat soluble vitamins (Leah 2009). About 20-25% of the total daily cholesterol production occurs in the liver; intestines, adrenal glands and reproductive organs being other sites for cholesterol synthesis (Pearson et al 2004).…”

Cardiovascular Risk Factors: Implications in Diabetes, Other Disease States and Herbal Drugs

“…It constitutes essentially structural component of membrane required in establishing proper membrane permeability and fluidity and is also a constituent of the outer layer of plasma lipoproteins. Cholesterol is the principal sterol synthesized by animals and transported in the blood plasma of all mammals (Leah, 2009). It is also an important component implicated in the manufacture of bile acids, steroid hormones, and vitamin D (Jain, 2005;Maxifield and Tabas, 2005;Hasimun, 2011).…”

Lipoproteins and Cardiovascular Diseases

“…The molecular basis of this regulation was set out by Michael Brown and Joseph Goldstein, earning them the Nobel Prize in Physiology and Medicine in 1985 (Leah, 2009). A key irreversible step of cholesterol synthesis is catalyzed by HMG-CoA reductase.…”

“…Cholesterol is a waxy steroid of fat that is produced in the liver or intestines. It is used to produce hormones and cell membranes and is transported in the blood plasma of all mammals (Leah, 2009). As an essential structural component of mammalian cell membranes, it is required to establish proper membrane permeability and fluidity.…”