Cholesterol Can be Lowered in Older Persons

Kaiser, Fran E.; Morley, John E.

doi:10.1111/j.1532-5415.1990.tb01604.x

Cited by 18 publications

(8 citation statements)

References 22 publications

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“…Paradoxically, low circulating cholesterol levels are predictive of death in older persons and in persons with heart disease [22].…”

Section: Mechanisms Underlying Anorexia Of Agingmentioning

confidence: 99%

Anorexia of Aging

Conte¹,

Cascino²,

Bartali³

et al. 2009

CNF

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The physiopathological decline in appetite and food intake known as "anorexia of aging" can lead to involuntary weight loss and protein-energy malnutrition, with devastating consequences in older men and women. Food intake can be influenced by numerous endogenous and exogenous factors, both physiological and pathological: mechanisms underlying age-related anorexia are multifactorial, and not completely understood. Early recognition of anorexia, nutritional and pharmacological interventions can help prevent the development of malnutrition and poor clinical outcome in the elderly.

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“…Paradoxically, low circulating cholesterol levels are predictive of death in older persons and in persons with heart disease [22].…”

Section: Mechanisms Underlying Anorexia Of Agingmentioning

confidence: 99%

Anorexia of Aging

Conte¹,

Cascino²,

Bartali³

et al. 2009

CNF

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“…Animal studies have further supported the concept that altering the lipid milieu may alter cognition, perhaps by modulating membrane fluidity 135 . Overall, these studies strongly question whether lowering cholesterol levels is a rational approach in persons over 70 years of age 136 . The policy of avoiding cholesterol‐lowering medications in older persons is further supported by a recent meta‐analysis of cholesterol lowering in middle‐aged persons, which failed to show a decrease in mortality 137 …”

Section: Nutritionmentioning

confidence: 99%

Major Issues in Geriatrics over the Last Five Years

Morley

1994

J American Geriatrics Society

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“…Twenty‐one years ago, Fran Kaiser and I published an editorial in this journal entitled “Cholesterol can be lowered in older persons. Should we care?” This editorial was written in response to a series of epidemiological articles suggesting that, in old persons, low cholesterol was associated with greater total mortality. In this issue of the Journal , Newson and colleagues found that higher total cholesterol and non‐high‐density lipoprotein cholesterol (HDL‐C) in older persons was associated with a lower risk of noncardiovascular and total mortality.…”

mentioning

confidence: 99%