Cholesterol-lowering and Anti-obesity Effects of Polymnia Sonchifolia Poepp. &amp; Endl. Powder in Rats Fed a High Fat-High Cholesterol Diet

김아라,; 이재준,; 이유미,; 정해옥,; 이명렬,

doi:10.3746/jkfn.2010.39.2.210

Cited by 21 publications

(17 citation statements)

References 11 publications

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“…Weight gain (g/fish) for fish fed the YC diet was significantly greater than that for fish fed the other diets. This is in contrast to Kim et al (2010b) who reported that dietary supplementation of 5 and 10% YC effectively lowered the weight gain of rats fed a high fat-high cholesterol diet. The GG, BB and Con diets also increased weight gain but to a lesser degree.…”

Section: Resultscontrasting

confidence: 54%

“…Crude lipid content of fish fed the YC diet was significantly higher than of fish fed the Con, GG, BB, PM, TT and BC diets, but not significant to fish fed the CJ diet. In contrast, Kim et al (2010b) reported that the dietary inclusion of YC could potentially reduce lipid storage of rats fed a high cholesterol diet as the YC supplement might improve serum, liver and adipose tissue lipid metabolism. Administration of green tea extract has been shown to lower total lipid content in rockfish (Hwang et al, 2013).…”

Section: Resultsmentioning

confidence: 93%

“…However, the weight gain of rats fed a high fat-high cholesterol diet supplemented with 10% YC was lower than of rats consuming an equal amount of control diet (Kim et al, 2010b) and there was no effect on weight gain, feed intake and FE of broiler chickens fed with the dietary inclusion of 0.5, 1 and 2% YC byproduct in a 5-week feeding trial (Kim, 2013). However, in the latter study the level of thiobarbituric acid reactive substance (TBARS) in chicken thigh meat decreased, and DPPH (1, 1-diphenyl-2-picrylhydrazyl) radical-scavenging activity increased in a dose-dependent manner.…”

Section: Resultsmentioning

confidence: 98%

“…The oral administration of TT lowered food intake of rats of both hypo-and hyper-energetic diets (Moreira et al, 2005). Supplementation of YC into the high fat-high cholesterol diet lowered rat feed consumption (Kim et al, 2010b). However, dietary inclusion of BC did not affect feed intake of broiler chickens and rats (Muller et al, 2012;Tomofuji et al, 2012).…”

Section: Resultsmentioning

confidence: 99%

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Kim¹,

Kim²,

Choi³

et al. 2016

Turk. J. Fish. Aquat. Sci.

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Whether the inclusion of the various sources of commercially available dietary additives [ginger (GG), cheonggukjang (CJ), blueberry (BB), persimmon (PM), tomato (TT), broccoli (BC) and yacon (YC)] has an effect on growth, body composition, and challenge test survival of juvenile rockfish Sebastes schlegeli was investigated. Twenty-four groups of 70 fish (1680 in total) were each fed one of eight experimental diets: a control diet (Con) without additives, and diets containing GG, CJ, BB, PM, TT, BC or YC. Fish were hand-fed to satiation twice daily for 7 weeks. At the end of this period, 20 fish from each tank were infected with Streptococcus parauberis and monitored for 10 days. Fish fed the YC diet had greater weight gain compared with fish fed the other diets. Feed efficiency and protein efficiency ratio of fish fed the TT and YC diets were higher than of fish fed other diets. Cumulative mortality of fish fed the GG, BB, and YC diets was lower than of fish fed the other diets on day 5 post infection. We conclude that yacon was the best dietary additive for improving rockfish weight gain, while ginger, blueberry, and yacon effectively lowered mortality of rockfish infected with S. parauberis.

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Section: Resultscontrasting

confidence: 54%

Section: Resultsmentioning

confidence: 93%

Section: Resultsmentioning

confidence: 98%

Section: Resultsmentioning

confidence: 99%

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Kim¹,

Kim²,

Choi³

et al. 2016

Turk. J. Fish. Aquat. Sci.

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“…The activities of GOT and GPT tend to increase according to the exogenous cholesterol contents from diet (35). Since these enzymatic activities in serum decreased significantly due to the supplementation of purslane powder in this experiment, it is expected that the adding of purslane powder to the hypercholesterolemic diet will be effective for the recovery of the hepatic function by the improvement of lipid metabolism or delaying the hepatic disorder.…”

Section: Got Gpt Alp and Ldh Activities In Serummentioning

confidence: 91%

Effects of Portulaca oleracea Powder on the Lipid Levels of Rats Fed a Hypercholesterolemia Inducing Diet

Lee¹,

Shin²,

Kang³

et al. 2011

JFN

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This study was initiated to investigate the effects of lyophilized purslane (Portulaca oleracea) powder (5% and 10%) on lipid levels in rats fed a hypercholesterolemia-inducing diet (1% cholesterol). During the four week study, there were no significant differences in either weight change or the food efficiency ratio between the group fed the hypercholesterol diet alone (HC) and the groups fed the purslane powder (HCPO-I and HCPO-II, 5% and 10% purslane, respectively). In serum, the levels of total lipid, total cholesterol and LDL-C decreased significantly for the group fed the 10% purslane powder (HCPO-II) in comparison with the group fed the 5% purslane powder (HCPO-I). The atherogenic index (AI) was reduced by about 51% for the group fed the 10% purslane powder (1.47) in comparison with the HC group (3.03). The activities of GOT, GPT, ALP and LDH decreased significantly for the groups fed the purslane powder in comparison with the HC group. Regarding liver tissue, the levels of total lipid, total cholesterol and triglyceride decreased significantly for the purslane powder-fed rats compared to the HC group. The fecal lipid profiles increased significantly as the amount of purslane powder was increased. Compared to the HC group, the fecal total cholesterol and triglyceride levels were higher in the group fed the 10% purslane powder by about 2.8 times and 2.3 times, respectively. For the serum and liver tissue, the content of lipid peroxide decreased significantly in the groups fed purslane powder compared to the HC group. The data from this experiment show an increase in the lipid levels discharged in feces, suggesting that the supplementation of purslane powder to a hypercholesterolemia-inducing diet reduces lipid levels.

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Simultaneous screening of dietary supplements for 25 anti‐hyperlipidemic substances using ultra‐performance liquid chromatography and liquid chromatography/electrospray ionization tandem mass spectrometry

Kim

Lim

Choi

et al. 2020

Rapid Comm Mass Spectrometry

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RationaleRecently, illegal dietary supplements containing unauthorized compounds have been seized and internationally publicized with a warning to avoid their consumption. This adulteration can be a serious threat to public health because of insufficient and reliable safety data as well as their undesirable side effects. It is, therefore, essential to rapidly and accurately develop and simultaneously validate analytical methods for these unauthorized anti‐hyperlipidemic substances.MethodsDietary supplements were screened simultaneously for 25 anti‐hyperlipidemic drugs using an ultra‐high‐performance liquid chromatography (UPLC) system with a photodiode array (PDA) detector and LC/electrospray ionization tandem mass spectrometry (LC/ESI‐MS/MS). The method validation, according to ICH guidelines, considered specificity, linearity, limit of detection (LOD), limit of quantification (LOQ), precision, accuracy, matrix effects, and stability for solid and liquid blank samples. The established UPLC‐PDA and LC/ESI‐MS/MS methods were applied to screen 103 dietary supplements for 25 anti‐hyperlipidemic substances.ResultsUsing the validated methods, the screened samples were found to contain peaks with similar retention times and PDA spectra. By comparing the calculated precursor‐product ion ratios with those of standards, lovastatin and lovastatin acid were detected at concentrations from LOQ to 4.12 mg/g and LOQ to 9.65 mg/g, respectively.ConclusionsThe developed UPLC‐PDA and LC/ESI‐MS/MS analytical methods were applied to 103 real samples, of which 13 samples were found to contain lovastatin and lovastatin acid. In view of the increasing demand for dietary supplements in the treatment of hyperlipidemic diseases, widespread use of these methods will contribute to consumer health by ensuring the safety of dietary supplements.

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Cholesterol-lowering and Anti-obesity Effects of Polymnia Sonchifolia Poepp. & Endl. Powder in Rats Fed a High Fat-High Cholesterol Diet

Cited by 21 publications

References 11 publications

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Effects of Portulaca oleracea Powder on the Lipid Levels of Rats Fed a Hypercholesterolemia Inducing Diet

Simultaneous screening of dietary supplements for 25 anti‐hyperlipidemic substances using ultra‐performance liquid chromatography and liquid chromatography/electrospray ionization tandem mass spectrometry

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