Cholesterol-lowering and Artherosclerosis Inhibitory Effect of Sibu Olive in Cholesterol Fed-rabbit

Nurulhuda, M. H.; Azlan, Azrina; Ismail, Amin; Amom, Zulkhairi; Shakirin, Faridah Hanim

doi:10.3923/ajb.2012.80.89

Cited by 11 publications

(10 citation statements)

References 12 publications

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“…In the study carried on broiler, it was found that the serum urea, creatinine, uric acid, triglyceride, total protein, glucose, K and Cl were not affected by the addition of rosehip, but cholesterol level decreased because of high cellulose content and flavonoids (Tekeli, 2014). In the different study, it has been reported that phenolic compounds such as flavonoids, anthocyanidins and anthocyanins reduced endogenous cholesterol absorption and synthesis (Nurulhuda et al, 2012). It is also emphasized that the RS may have hypocholesterolemic activity because it is rich in phenolic compounds.…”

Section: Resultsmentioning

confidence: 99%

The Effect of Rosehip Seed Supplementation into Laying Hens Diets on Performance, Egg Quality Traits, Yolk Lipid Profile and Serum Parameters

Kaya¹,

Kaya²,

Esenbuğa³

et al. 2019

Alınteri Zirai Bilimler Dergisi

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A B S T R A C TThis study was carried out to determine the effect of dietary rosehip seed (RS) supplementation into layer diets at different levels on performance, egg quality traits and some serum parameters. A total of 72 Lohmann layers, 46 weeks old, were divided into three treatment groups. The control group was fed with commercial layer diet (K), and the other two groups were fed with basal diet + 10% ground rosehip seeds (K1) and basal diet + 15% ground rosehip seeds (K2) for 12 weeks. The water and feed were provided as ad-libitum during the trial. The rosehip seed supplementation level at 15% into layer diets increased the feed consumption and egg yield (p<0.05), and decreased the damaged egg ratio. Though some egg quality traits such as the yolk colour, shell thickness and shell weight increased (p<0.05) in eggs from K2 group, there were no significant differences (p> 0.05) among the groups in respect to other egg quality traits such as shape index, shell strength, albumen and yolk indexes and Haugh unit values. Total cholesterol, cholesterol esters, free fatty acids and triglyceride contents in the egg yolks from treatment groups were not affected by dietary treatments (p> 0.05). Serum parameters such as albumin, total cholesterol, VLDL, triglyceride and ALT values increased (p <0.05) with the RS supplementation at level of 15% into layer diet. Results showed that rosehip seed supplementation into layer diets may be beneficial to improve egg quality traits especially such as shell thickness and to decrease damaged egg ratio. But further investigations are needed to clarify the use of rosehip seed in layer diets and its effects on performance, egg quality and serum parameters.

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Section: Resultsmentioning

confidence: 99%

The Effect of Rosehip Seed Supplementation into Laying Hens Diets on Performance, Egg Quality Traits, Yolk Lipid Profile and Serum Parameters

Kaya¹,

Kaya²,

Esenbuğa³

et al. 2019

Alınteri Zirai Bilimler Dergisi

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“…In fact, the presence of phytochemicals, in addition to vitamins and provitamins, has been considered of great nutritional interest in the prevention of chronic diseases, such as cancer, arteriosclerosis, nephritis, diabetes mellitus, rheumatism, ischemic and cardiovascular diseases and also in the aging process, in which oxidants or free radicals are involved (Chu et al, 2002;Pulido et al, 2000;Behl and Moosmann, 2002). Natural anti-oxidants have been shown to offer a vast array of health effects including lowering the level of blood cholesterol which is correlated with body cholesterol (Nuhulhuda et al, 2012) and there is now an increased focus on defining natural products that are capable of mediating the desired effect. One such product is cabbage (Brassica oleracea), which contains several phytochemical compounds which act as antioxidants, stimulate detoxification enzymes, stimulate the immune system, positively affect the expression of hormones and act as antibacterial and antiviral agent.…”

Section: Introductionmentioning

confidence: 99%

Nutritive effect of cabbage (<i>Brassica oleracea</i>) on growth, obesity, lipidaemia and haematology in broiler and pullet chickens

Adesina¹,

Toye²

2015

Global Journal of Agricultural Sciences

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Efficacy of cabbage (Brassica oleracea) for ameliorating the adverse metabolic syndrome side-effects of genetically improved growth rate in chickens was examined. Sixty-four (64) day-old birds (32 Marshall Broilers and 32 Harco Black Pullets) were randomly assigned to groups of eight genotype-matched birds in a 2-factor layout within a Completely Randomized Design (CRD). Within genotype, each group was randomly assigned one of four diets (basal/control diet containing 0% cabbage, and, basal diet supplemented with 3%, 6% or 12% cabbage) for 4 weeks. All birds were fed an un-supplemented Broiler finisher diet from week 4 -8. Bodyweight and Body Mass Index (BMI) were determined weekly. Blood Packed Cell Volume (PCV), Haemoglobin (Hb), White Blood Cells (WBC), Red Blood Cells (RBC), neutrophils, lymphocytes, monocytes, basophils and eosinophils), Total serum Cholesterol (TC), High Density Lipoprotein (HDL) and Low Density Lipoprotein (LDL) were determined at age 4 weeks. Irrespective of diet or age, Broilers exhibited significantly greater (p<0.05) body weight, adiposity, and lipidaemia than Pullets, and no interactions between cabbage and genotype were observed for the same traits. Dietary cabbage at 3%, irrespective of genotype significantly (p<0.05) improved body weight beyond week 5 while no significant effect was observed on body fatness as measured by BMI. Cabbage supplementation suppressed broiler eosinophil levels, indicating effects on mediators of innate immune surveillance, but did not influence any other blood haematological parameter, though Broilers exhibited higher (p<0.05) total WBC count and proportion (%) of WBC represented by neutrophils, basophils and eosinophils. In Contrast, Pullets exhibited higher RBC, PCV, and Hb, and lymphocyte and monocyte differential counts. Dietary Cabbage had a nutrigenetic effect on cholesterol: Reduced TC and LDL in Broilers in contrast to its effect in increasing the same lipids in Pullets. Cabbage however lowered HDL Cholesterol (p<0.05) in both genotypes, though the threshold of effect was higher (12%) in Pullets (3%). Thus Cabbage is effective in lowering heart disease risk through lowering of lipidaemia in Broilers, and improves bodyweight at market age (7-8 weeks) at 3% dietary supplementation level.

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“…The cholesterol lowering effect of the defatted dabai powder has proven its protective effect in hypercholesterolemic condition [8, 25]. In this study, the use of defatted dabai peel extract at 2000 mg/day has successfully reduced oxidative stress condition in the hypercholesterolemic rabbits.…”

Section: Resultsmentioning

confidence: 76%

Antioxidative and Cardioprotective Properties of Anthocyanins from Defatted Dabai Extracts

Khoo

Azlan

Nurulhuda

et al. 2013

Evidence-Based Complementary and Alternative Medicine

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This study aimed to determine anthocyanins and their antioxidative and cardioprotective properties in defatted dabai parts. Anthocyanins in crude extracts and extract fractions of defatted dabai peel and pericarp were quantified using UHPLC, while their antioxidant capacity and oxidative stress inhibition ability were evaluated by using DPPH and CUPRAC assays as well as linoleic acid oxidation system, hemoglobin oxidation, and PARP-1 inhibition ELISA. Cardioprotective effect of the defatted dabai peel extract was evaluated using hypercholesterolemic-induced New Zealand white rabbits. Six anthocyanins were detected in the defatted dabai peel, with the highest antioxidant capacities and oxidative stress inhibition effect compared to the other part. The defatted dabai peel extract has also inhibited lipid peroxidation (plasma MDA) and elevated cellular antioxidant enzymes (SOD and GPx) in the tested animal model. Major anthocyanin (cyanidin-3-glucoside) and other anthocyanins (pelargonidin-3-glucoside, malvidin-3-glucoside, cyanidin-3-galactoside, cyanidin-3-arabinoside, and peonidin-3-glucoside) detected in the defatted dabai peel are potential future nutraceuticals with promising medicinal properties.

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Cholesterol-lowering and Artherosclerosis Inhibitory Effect of Sibu Olive in Cholesterol Fed-rabbit

Cited by 11 publications

References 12 publications

The Effect of Rosehip Seed Supplementation into Laying Hens Diets on Performance, Egg Quality Traits, Yolk Lipid Profile and Serum Parameters

The Effect of Rosehip Seed Supplementation into Laying Hens Diets on Performance, Egg Quality Traits, Yolk Lipid Profile and Serum Parameters

Nutritive effect of cabbage (<i>Brassica oleracea</i>) on growth, obesity, lipidaemia and haematology in broiler and pullet chickens

Antioxidative and Cardioprotective Properties of Anthocyanins from Defatted Dabai Extracts

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