1988
DOI: 10.1093/jn/118.9.1116
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Choline-Deficient Diet Increases Z Protein Concentration in Rat Liver

Abstract: Feeding rats a diet deficient in choline results in fatty liver within 1 d. We studied the effect of short-term (1-3 d) choline deficiency on rat liver Z protein (fatty acid-binding protein). Groups of three females Sprague-Dawley rats were fed ad libitum a purified diet lacking choline and L-methionine or were supplemented with 0.2% choline chloride and 0.82% L-methionine. Animals were killed after 1, 2 or 3 d of consuming control or experimental diets and hepatic Z protein was prepared. Z protein in livers f… Show more

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Cited by 17 publications
(1 citation statement)
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“…It acts as a methyl donor and plays an important role in phospholipid formation for lipoprotein metabolism. Choline deficiency may rapidly induce fatty liver in rats (Dutta-Roy, 1988). If choline is insufficient in the periparturient dairy cow, the accumulation of triglycerides may increase.…”
Section: Introductionmentioning
confidence: 99%
“…It acts as a methyl donor and plays an important role in phospholipid formation for lipoprotein metabolism. Choline deficiency may rapidly induce fatty liver in rats (Dutta-Roy, 1988). If choline is insufficient in the periparturient dairy cow, the accumulation of triglycerides may increase.…”
Section: Introductionmentioning
confidence: 99%