Cholinergic signalling mechanisms and early implant healing phases in healthy versus generalized aggressive periodontitis patients: A prospective, case–control study

Meriç, Pınar; Buduneli, Nurcan; Kanmaz, Burcu; Gürlek, Önder; Çömlekoğlu, M. Erhan; Calvert, Gareth; Lappin, David F.; Nile, Christopher J.

doi:10.1111/jcpe.13185

Cited by 3 publications

(1 citation statement)

References 51 publications

(79 reference statements)

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“…8 Periodontal diseases such as aggressive periodontitis negatively affect implant osseointegration. 9 Thus, clinicians should save such teeth rather than extract them and replace them with implants. 10 Comparing the survival rate between endodontically treated teeth with poor prognosis and implants placed in previously diseased sites showed that the survival rate of endodontically treated teeth was comparatively higher than implants.…”

Section: Introductionmentioning

confidence: 99%

<p>Treatment of an Endo-Perio Lesion with Ozone Gas in a Patient with Aggressive Periodontitis: A Clinical Case Report and Literature Review</p>

Makeeva

Даурова

Byakova

et al. 2020

CCIDE

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The pulp and periodontium have obvious relationships that have been described in many studies. Pulp infections may affect periodontal tissues and vice versa. Teeth with endo-perio lesions have a worse prognosis than isolated endodontic or periodontal lesions. Elimination of endodontic and periodontal infections is essential for successful treatment, so co-operation between endodontists and periodontists is necessary. In this clinical case, a 44-year-old male presented with primary periodontal disease with secondary endodontic involvement in his lower right canine because of aggressive periodontitis. There was 10 mm of clinical attachment loss and 8 mm periodontal pocket mesial from the tooth and bone radiolucency periapical and lateral from the root. Periodontal therapy was followed by endodontic treatment. Periodontal therapy included root scaling and planing, treatment of the periodontal pocket with ozone gas, systemic antibiotics, oral hygiene instructions, and chlorhexidine rinsing. Endodontic therapy included root canal instrumentation with rotary endodontic files, irrigation, root canal treatment with ozone gas, and obturation with lateral compaction. Radiographs at a 6-month follow-up appointment showed complete healing of the periapical lesion and alveolar bone lateral to the root. Using an interdisciplinary approach to treat endo-perio lesions provides favorable clinical outcomes. Ozone therapy is beneficial for the successful treatment of endo-perio lesions with narrow periodontal pockets in patients with aggressive periodontitis and poor prognosis.

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Section: Introductionmentioning

confidence: 99%

<p>Treatment of an Endo-Perio Lesion with Ozone Gas in a Patient with Aggressive Periodontitis: A Clinical Case Report and Literature Review</p>

Makeeva

Даурова

Byakova

et al. 2020

CCIDE

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Pro-Inflammatory Cytokines Expressed During the Initial Phases of Osseointegration: A Systematic Review

Baker,

Fernandes,

Figueredo

2024

JCM

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Background: Identifying patients with a strong pro-inflammatory phenotype may allow clinicians to underpin high-risk individuals based on early inflammatory marker profiles and to personalize approaches to preventative treatments. Aim: The objective of this systematic review is to synthesize the results of previous studies on osseointegration to show which pro-inflammatory cytokines and chemokines have been detected and quantified during the initial phase of osseointegration. Material and methods: PubMed, Embase, Scopus, ISI Web of Science, and Cochrane Library were searched for articles published until August 2024. A descriptive summary was produced to explain study variations, including patients’ characteristics and results. The methodological quality of each included study was assessed based on Downs and Black’s checklist. Results: 30 studies were selected for inclusion. In total, 710 patients received 1329 implants (an average of 1.87 implants per participant). A total of 32 biomarkers were analyzed. The overall trend observed in levels of pro-inflammatory cytokines and chemokines appears to be an early peak, followed by a progressive reduction in levels throughout the observation periods. Conclusion: The available evidence suggests that a strong expression of pro-inflammatory biomarkers is a feature of osseointegration, and an over- or underexpression of certain biomarkers could have an effect on early marginal bone levels. Several of these markers are mechanistically implicated with implant pathology; however, the prognostic value of early cytokine expression and correlation with long-term clinical outcomes requires further research.

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An Overview On Periodontal – Endodontic Lesions Diagnosis And Management: A Literature Review

Shrwani¹,

Alshammari²,

AlShammari³

et al. 2021

Ann. Dent. Spec

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Cholinergic signalling mechanisms and early implant healing phases in healthy versus generalized aggressive periodontitis patients: A prospective, case–control study

Cited by 3 publications

References 51 publications

<p>Treatment of an Endo-Perio Lesion with Ozone Gas in a Patient with Aggressive Periodontitis: A Clinical Case Report and Literature Review</p>

<p>Treatment of an Endo-Perio Lesion with Ozone Gas in a Patient with Aggressive Periodontitis: A Clinical Case Report and Literature Review</p>

Pro-Inflammatory Cytokines Expressed During the Initial Phases of Osseointegration: A Systematic Review

An Overview On Periodontal – Endodontic Lesions Diagnosis And Management: A Literature Review

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