Cholinesterase inhibitory activity and chemical constituents of Stenochlaena palustris fronds at two different stages of maturity

Chear, Nelson Jeng Yeou; Khaw, Kooi Yeong; Murugaiyah, Vikneswaran; Lai, Choon Sheen

doi:10.1016/j.jfda.2015.12.005

Cited by 42 publications

(38 citation statements)

References 38 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…TFC in methanolic extract of mature frond of kelakai (50.356 g QE/100 g) was higher than young frond (20.566 g QE/100 g) [13]. It was contrary to the present study which exposed that TFC in ethanolic extract of YLs, OLs, and root extract of kelakai were 1.99, 2.63, and 3.55 g QE/100 g, respectively, meanwhile TCC in ethanolic extract of YLs, OLs, and root extracts of kelakai were 7.28, 17.03, and 7.61 g BE/100 g, respectively.…”

Section: Discussionmentioning

confidence: 81%

“…Antioxidant activity can be related with the TPC [24,25]. Previous research by Chear et al [13] revealed that TPC in methanolic extract of young frond and mature frond of kelakai were 9.415 and 25.2 g GAE/100 g, respectively. TPC in water extracts of young sterile frond, mature sterile frond, young fertile frond, and mature fertile frond were 4.258, 5.169, 4.168, and 1.878 g GAE/100 g, respectively [19].…”

Section: Discussionmentioning

confidence: 95%

“…The ortho di-OH position at C-3'-C-4' had the highest influence to antioxidant activity of flavonoid [26]. Study by Chear et al [13] reported that mature sterile frond of S. palustris contained kaempferol glycosides. In Fig.…”

Section: Discussionmentioning

confidence: 96%

Section: Introductionmentioning

confidence: 99%

“…The previous researches [3,8,11,12] revealed that DPPH, ABTS, and FRAP can be performed to determine antioxidant activity of fruits, vegetables, and food. Kelakai (Stenochlaena palustris), empirically used in Central Kalimantan for antiaging, contained many derivates of kaempferol glycosides which can act as antioxidant [13].The objectives of this research were to evaluate antioxidant activities in various polarity extracts (n-hexane, ethyl acetate, and ethanol) from different parts of kelakai grown in Central Kalimantan -Indonesia, using DPPH and FRAP assays and correlations of TPC, TFC, and total carotenoid content (TCC) with their antioxidant activities. …”

mentioning

confidence: 99%

See 4 more Smart Citations

Antioxidant Activities From Various Extracts of Different Parts of Kelakai (Stenochlaena Palustris) Grown in Central Kalimantan - Indonesia

Fidrianny¹,

Kusmardiyani²,

Novita³

2016

Asian J Pharm Clin Res

View full text Add to dashboard Cite

Objectives: The aims of this research were to determine antioxidant activity from various extracts of different parts of kelakai (Stenochlaena palustris [Burm.f.] Bedd) using two antioxidant testing methods, which were 2,2-diphenyl-1-picrylhydrazyl (DPPH) and ferric reducing antioxidant power (FRAP), and correlation of total phenolic contents (TPC), total flavonoid contents (TFC), and total carotenoid contents (TCC) with their inhibitory concentration 50% (IC 50 ) of DPPH and exhibitory concentration 50% (EC 50 ) of FRAP.Methods: Sample was extracted by reflux using different polarity solvents. The extracts were evaporated using vacuum rotary evaporator. Antioxidant activities were tested using DPPH and FRAP assays, determination of TPC, TFC, and TCC was carried out by ultraviolet-visible spectrophotometry, and correlation with their IC 50 of DPPH and EC 50 of FRAP capacities was analyzed by Pearson's method.Results: Ethanolic root extract of kelakai (S. palustris) had the lowest IC 50 of DPPH scavenging activity 0.8 µg/ml and the lowest EC 50 of FRAP capacity 5.4 µg/ml. Ethanolic kelakai root extract demonstrated the highest phenolic content, ethyl acetate young leaves extract had the highest flavonoid content, and the highest carotenoid content was given by n-hexane root extract. There was significantly negative correlation between TPC in root extract of kelakai with their IC 50 of DPPH and EC 50 of FRAP. Conclusions:All different extracts of kelakai parts were categorized as very strong antioxidants by DPPH method. Phenolic compounds in kelakai root extract were the major contributor in antioxidant activities by DPPH and FRAP methods. DPPH and FRAP showed linear results in antioxidant activities of root kelakai extract.Keywords: Antioxidant, 2,2-diphenyl-1-picrylhydrazyl, Ferric reducing antioxidant power, Stenochlaena palustris, Young leaves, Old leaves, Root. INTRODUCTIONPhenolic compounds and flavonoids are commonly found in many plants, which have many effects such as antioxidant activity and antibacterial activity [1][2][3][4]. Phenolic, flavonoid, and carotenoid compounds might be having antioxidant activity [5]. Antioxidant has many benefits to prevent the excessive of free radical in oxidative stress which can cause many degenerative diseases. Consumption of fruits and vegetables can prevent negative effect of oxidative stress because they contain phenolic, flavonoid, and carotenoid compounds, which have antioxidant capacity [6]. Previous researches represented that total phenolic content (TPC) and total flavonoid content (TFC) could be correlated to their antioxidant activities [7][8][9]. Plants included sweet potatoes, guava, lemon grass, tea, and legumes contained phenolic and flavonoid compounds [1-3,10,11].Ferric reducing antioxidant power (FRAP), 2,2'-azino-bis (3-ethylbenzthiazoline-6-sulfonic acid (ABTS), and 2,2-diphenyl-1-picrylhydrazyl (DPPH) methods could be used to observe antioxidant activity in many plants extracts [4,10,11]. The previous researches [3,8,11,12] revealed that DPP...

show abstract

Section: Discussionmentioning

confidence: 81%