Cholinesterases and biogenic monoamines in ganglion semilunare (Gasseri)

Lukáš, Zdeněk; Čech, Svatopluk; P, Burianek

doi:10.1007/bf00303627

Cited by 14 publications

(1 citation statement)

References 7 publications

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“…Out of the six different types of monoamines, catecholamines [dopamine (DA), noradrenaline (NA) and adrenaline (A)] are the most important group. The earliest evidence for the catecholaminergic innervation of the TG sprang from the works of Santini (1966) and Lukás et al (1970). In these initial studies by using immunocytochemistry with antiserum against tyrosine hydroxylase (TH), the rate-limiting enzyme of catecholamine synthesis, the immunostained neurons within the ganglion were proposed to be DAergic.…”

Section: Monoaminesmentioning

confidence: 99%

The Neurochemical Anatomy of Trigeminal Primary Afferent Neurons

Lazarov¹

2012

Neuroscience - Dealing With Frontiers

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Section: Monoaminesmentioning

confidence: 99%

The Neurochemical Anatomy of Trigeminal Primary Afferent Neurons

Lazarov¹

2012

Neuroscience - Dealing With Frontiers

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Substance P in the vagal sensory ganglia: Localization in cell bodies and pericellular arborizations

Katz

Karten

1980

J of Comparative Neurology

142

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The distribution of Substance P-like immunoreactivity in the jugular and nodose ganglia of rabbits and pigeons has been studied using immunocytochemical staining techniques. Substance P-like immunoreactivity is localized to neuronal cell bodies and processes in the jugular and nodose ganglia, and to pericellular fiber plexi in the nodose ganglia of both species. The numbers and sizes of cells which exhibited Substance P-like immunoreactivity in each ganglion were determined using quantitative morphometric techniques. The distribution of Substance P-like immunoreactivity in the rabbit and pigeon vagal sensory ganglia is characterized by several general features. In most of the ganglia, immunoreactive neurons factor into discrete types which can be distinguished from one another, and from non-immunoreactive neurons, by size. In addition, immunoreactive nodose and jugular ganglion cells, respectively, are distinguishable on the basis of size. Finally, a considerably high percentage of immunoreactive neurons is found in the jugular ganglion than in the nodose ganglion. Substance P-like immunoreactivity was also seen in pericellular fiber plexi which encircle individual neurons in the nodose ganglion of rabbits and pigeons. These plexi are composed of varicose fibers which appear to terminate as boutons on the surface of the cells which they encircle. The distribution of Substance P-like immunoreactivity within the vagal sensory ganglia is discussed with respect to the possible peripheral targets and functions of Substance P-containing vagal afferents. Our findings suggest that Substance P-containing vagal sensory neurons are involved in a variety of visceral and somatic afferent functions.

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Overexpression of nerve growth factor in transgenic mice induces novel sympathetic projections to primary sensory neurons

Davis

Albers

Seroogy

et al. 1994

J of Comparative Neurology

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Peripheral nerve crush induces novel projections from noradrenergic sympathetic neurons to sensory ganglia, and it has been suggested that these projections provide an anatomical substrate for chronic pain syndromes that occur after nerve injury. The present study demonstrates that novel sympathetic projections to sensory neurons are also induced in transgenic mice that overexpress nerve growth factor (NGF) in the skin. Specifically, a large proportion of trigeminal neurons in NGF transgenic mice were innervated by tyrosine hydroxylase (TH)-positive pericellular arborizations that were seen only rarely in controls. Electron microscopic analysis of NGF transgenic mice revealed that trigeminal neurons were surrounded by numerous axonal varicosities containing synaptic specializations. Removal of the superior cervical ganglion abolished TH-immunoreactive arborizations in the ipsilateral trigeminal ganglion confirming that these fibers were sympathetic axons. A two-site enzyme-linked immunosorbent assay revealed that transgenic ganglia contained a tenfold increase in NGF peptide compared to controls. However, reverse transcriptase polymerase chain reaction analysis showed no apparent expression of transgene mRNA in sensory ganglia, suggesting that the additional NGF was derived from increased NGF expression in the skin. These results indicate that NGF can induce novel sympathetic projections to sensory neurons in vivo and suggests a model in which increased NGF expression plays a role in the development of sympathetic hyperalgesia after nerve injury.

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Cholinesterases and biogenic monoamines in ganglion semilunare (Gasseri)

Cited by 14 publications

References 7 publications

The Neurochemical Anatomy of Trigeminal Primary Afferent Neurons

The Neurochemical Anatomy of Trigeminal Primary Afferent Neurons

Substance P in the vagal sensory ganglia: Localization in cell bodies and pericellular arborizations

Overexpression of nerve growth factor in transgenic mice induces novel sympathetic projections to primary sensory neurons

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