Chondroid Chordoma of the Lateral Skull Base

Rossiello, Raffaele; Ferrara, G; Varricchio, Attilio; Baldi, Alfonso; Motta, Sergio; Motta, G

doi:10.1159/000055722

Cited by 7 publications

(3 citation statements)

References 14 publications

(30 reference statements)

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“…Histologically, chordoma consists of epithelial cells with abundant, foamy cytoplasm, resembling the cells in adenocarcinoma (24). Chondroid chordomas have morphologic features similar to those of typical chordomas except the additional features of cartilagenous foci resembling those of chondroma or conventional chondrosarcoma (25). Parachordoma resembles chordoma histologically with nests of uniform-appearing, vacuolated epithelioid cells deposited in a myxochondroid matrix, however, with a wider range of appearance (26,27).…”

Section: Discussionmentioning

confidence: 99%

Primary Intracranial Myxoid Chondrosarcoma: Report of a Case and Review of the Literature

Kim

Park

et al. 2003

J Korean Med Sci

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Section: Discussionmentioning

confidence: 99%

Primary Intracranial Myxoid Chondrosarcoma: Report of a Case and Review of the Literature

Kim

Park

et al. 2003

J Korean Med Sci

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“…Chordoma typically originate in the clivus and are therefore generally located more centrally, whereas chondrosarcoma arise in the petroclival fissure and therefore occur more laterally. [ 38 ] Unfortunately, this is not a distinctive feature, as lateral skull base chordoma have also been described [ 94 , 95 ]. On CT, chondrosarcoma may show a typical ‘ring-and-arc’ chondroid matrix mineralization [ 96 ].…”

Section: Differential Diagnosismentioning

confidence: 99%

State-of-the-Art Imaging in Human Chordoma of the Skull Base

Santegoeds

Temel

Beckervordersandforth

et al. 2018

Curr Radiol Rep

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Purpose of ReviewChordoma are rare tumours of the axial skeleton which occur most often at the base of the skull and in the sacrum. Although chordoma are generally slow-growing lesions, the recurrence rate is high and the location makes it often difficult to treat. Both computed tomography (CT) and magnetic resonance imaging (MRI) are crucial in the initial diagnosis, treatment planning and post-treatment follow-up.Recent FindingsBasic MRI and CT characteristics of chordoma were described in the late 1980s and early 1990s. Since then, imaging techniques have evolved with increased resolution and new molecular imaging tools are rapidly evolving. New imaging tools have been developed not only to study anatomy, but also physiologic changes and characterization of tissue and assessment of tumour biology. Recent studies show the uptake of multiple PET tracers in chordoma, which may become an important aspect in the diagnosis, follow-up and personalized therapy.SummaryThis review gives an overview of skull base chordoma histopathology, classic imaging characteristics, radiomics and state-of-the-art imaging techniques that are now emerging in diagnosis, treatment planning and disease monitoring of skull base chordoma.

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“…Chordoma typically originate in the clivus and are therefore generally located more centrally, whereas chondrosarcoma arise in the petroclival fissure and therefore occur more laterally. (38) Unfortunately, this is not a distinctive feature, as lateral skull base chordoma have also been described (94,95). On CT, chondrosarcoma may show a typical 'ring-and-arc' chondroid matrix mineralisation (96).…”

Section: Figure 3: Imaging Of a Well-defined Intraosseous Lesion In The Base Of The Skull Ct Imaging Of The Clivus In Axial (A) And Sagitmentioning

confidence: 99%

A journey of skull base chordoma

Santegoeds¹

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Chondroid Chordoma of the Lateral Skull Base

Cited by 7 publications

References 14 publications

Primary Intracranial Myxoid Chondrosarcoma: Report of a Case and Review of the Literature

Primary Intracranial Myxoid Chondrosarcoma: Report of a Case and Review of the Literature

State-of-the-Art Imaging in Human Chordoma of the Skull Base

A journey of skull base chordoma

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