Chondroitin sulfate hydrogels based on electrostatic interactions with enhanced adhesive properties: exploring the bulk and interfacial contributions

Abstract

<p>Adhesive polysaccharide gels have highlighted their potential in biomedicine, tissue engineering, and wearable/implantable devices due to their tissue adhesive nature and excellent biocompatibility.</p>

Synergistic complexation of phenol functionalized polymer induced in situ microfiber formation for 3D printing of marine-based hydrogels

“…During the elongation/recovery cycles, the DCCA hydrogel could maintain its structure while the hydrogel's adhesiveness prevented it from falling off due to the presence of electrostatic interaction between the polymers. 45 Our results demonstrated that DCCA hydrogel has high mechanical strength, toughness, flexibility, and moldability as an injectable hydrogel for clinical applications with a minimally invasive approach for regenerating irregular-shaped defects, particularly wound healing applications. As a biopolymer-based hydrogel without using any synthetic polymer or harmful crosslinking agent, the approach used in this study could open new insights into the design and development of bio-based hydrogels for biomedical applications.…”

“…4e). During the elongation/recovery cycles, the DCCA hydrogel could maintain its structure while the hydrogel's adhesiveness prevented it from falling off due to the presence of electrostatic interaction between the polymers 45 .…”

Polymer Pressure‐Sensitive Adhesive with A Temperature‐Insensitive Loss Factor Operating Under Water and Oil

“…The wetting environment may lead to the failure of pressure‐sensitive adhesion because the hydration of the polymers or swelling of the adhesive will hinder the formation of the interactions between the adhesive and target surface; therefore, strong adhesion is usually achieved in the dry state. [ 1 ] Recently, increasing studies have been focused on the engineering underwater adhesives and different methods such as surface drainage architecture design, [ 2–4 ] catechol chemistry, [ 5–7 ] hydrophobic adjustment, [ 8,9 ] water‐displacing [ 10,11 ] was proposed. However, many of the adhesives are only used at room temperature and their underwater adhesion performance under extreme temperature are unknown or unexplored.…”

“…surface; therefore, strong adhesion is usually achieved in the dry state. [1] Recently, increasing studies have been focused on the engineering underwater adhesives and different methods such as surface drainage architecture design, [2][3][4] catechol chemistry, [5][6][7] hydrophobic adjustment, [8,9] water-displacing [10,11] was proposed. However, many of the adhesives are only used at room temperature and their underwater adhesion performance under extreme temperature are unknown or unexplored.…”

“…There are three key rules to achieve robust pressure-sensitive adhesion: (i) the polymer chains can diffuse across the surface of the target substrate within the reasonable timescales; [22] (ii) formation of sufficient interactions between the polymer chains and the target surface; [1] (iii) effective energy dissipation within the adhesive. [23,24] Therefore, the viscoelasticity of the polymer is very crucial.…”