2024
DOI: 10.2183/pjab.100.019
|View full text |Cite
|
Sign up to set email alerts
|

Chondroitin sulfate proteoglycan 4: An attractive target for antibody-based immunotherapy

Tomohiro KUROKAWA,
Kohzoh IMAI

Abstract: Multifunctional molecules involved in tumor progression and metastasis have been identified as valuable targets for immunotherapy. Among these, chondroitin sulfate proteoglycan 4 (CSPG4), a significant tumor cell membrane-bound proteoglycan, has emerged as a promising target, especially in light of advances in chimeric antigen receptor (CAR) T-cell therapy. The profound bioactivity of CSPG4 and its role in pivotal processes such as tumor proliferation, migration, and neoangiogenesis underline its therapeutic p… Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...

Citation Types

0
0
0

Year Published

2024
2024
2024
2024

Publication Types

Select...
1

Relationship

0
1

Authors

Journals

citations
Cited by 1 publication
references
References 76 publications
0
0
0
Order By: Relevance