Chondromyxoid Fibroma

Abstract

Chondromyxoid fibroma is an uncommon benign cartilaginous tumor accounting for less than 1% of all bone tumors. The classic site of involvement is the metaphyseal region of long tubular bones, usually presenting in the second to third decades of life with nonspecific pain and swelling of the affected part. This case is an interesting incidental finding in a juvenile hallux abductovalgus deformity with no prodrome, eccentrically located in the diaphysis of the first metatarsal. Early detection and complete surgical resection are valuable in preventing recurrence in the affected bone. ACFAS Level of Clinical Evidence: 4.

Chondromyxoid Fibroma of the Skull Base Invading the Occipitocervical Junction: Report of a Unique Case and Discussion

“…It typically affects males more than females with a preponderance for those in their second and third decade. 2 The occurrence of this tumor in the skull base or cervical spine is rare; it most commonly arises in the metaphyseal region of long bones. 2 The rarity of this tumor makes it seldomly suspected preoperatively and may also make histological confirmation challenging.…”

“…2 The occurrence of this tumor in the skull base or cervical spine is rare; it most commonly arises in the metaphyseal region of long bones. 2 The rarity of this tumor makes it seldomly suspected preoperatively and may also make histological confirmation challenging. We present the first case of CMF originating in the clivus and extending into the atlas, requiring combined resection and stabilization surgery.…”

A Rare Case of Epiphyseal Chondromyxoid Fibroma of the Proximal Tibia

“…On T2-weighted spin echo images, it has been described as having multilobular patterns and high signal intensity, and these features are similar to the characteristics found in hyaline cartilage bone tumors (9-11). However, for CMFs, the high signal intensity on the T2-weighted images is probably pathologically related to the abundant myxoid stroma maintained by thin fibrous tissue in a multilobular pattern; this tumor may show hyaline cartilage differentiation (4, 5, 9-11). The MR imaging appearance of CMF can be very heterogeneous; and, its polymorphologic appearance depends on the different degrees of cellularity and the presence of varying amounts of myxoid and fibrous tissue (10).…”

“…The MR imaging appearance of a CMF has been described in a few reports (9-11). On T2-weighted spin echo images, it has been described as having multilobular patterns and high signal intensity, and these features are similar to the characteristics found in hyaline cartilage bone tumors (9-11).…”

“…In addition, the lesion shows characteristic high signal intensity foci of the hyaline cartilage on T2-weighted MR images. In very rare cases, the tumor occurs in an epiphysis where the lesion tends to involve almost the entire epiphysis in contrast to CMF (2, 6, 11). Giant cell tumor (GCT) is an epiphyseal lesion without calcification in a mature skeleton, and is seldom encountered in a patient younger than age 20 years or prior to epiphyseal closure (2).…”