Chondromyxoid Fibroma of Bone

Feldman, Frieda; Hecht, H.; Johnston, Austin D.

doi:10.1148/94.2.249

Cited by 108 publications

(46 citation statements)

References 18 publications

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“…A female preponderance was observed in patients with cervical spinal CMF, with C2 being most commonly affected. The most common clinical manifestation reported was neck pain [12][13] . Radiologically CMF appears as a well-defined lytic lesion with lobulated margins, a sclerotic ring, and septations.…”

Section: Discussionmentioning

confidence: 99%

“…Radiologically CMF appears as a well-defined lytic lesion with lobulated margins, a sclerotic ring, and septations. Occasionally, periosteal extension may occur due to fusiform expansion of the bone and calcifications are uncommon 13 . The radiological exam can be useful to try to differentiate benign chondroid tumors from malignant chondroid tumors in the preoperative period.…”

Section: Discussionmentioning

confidence: 99%

“…CMF may also be confused with FD due to the presence of myxoid elements, especially if no lobulations are presented 5 . One of the challenges in treating CMF is that a symptomatic spinal mass is approached as malignant, with the goal of being complete resected and fusion when necessary, as in this case 9,11,13 . Sometimes complete tumor resection is not possible because of the proximity to a neural or vascular structure and in such cases surgeons should perform other types of surgical approach when possible, as in this case, in order to try to remove as much is possible.…”

Section: Discussionmentioning

confidence: 99%

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Chondromyxoid fibroma of C1: first case report

et al. 2012

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Background: Chondromyxoid fibroma (CMF) is a rare, benign primary bone tumor. The cervical spine is an uncommon site for this tumor, with only 10 reported cases to date and none involving the first cervical vertebra (C1). Case Report: Female patient, 25-year-old monozygotic female twin, presented with cervical pain. Radiographic imaging demonstrated a contrast-enhanced, right-sided lytic lesion of the insufflated type in C1, with a punched-out appearance and extending to the anterior arch. A postero-lateral and a posterior approach were performed in two steps to resect the tumor followed by occipitocervical fixation. Pathology confirmed the diagnosis of CMF. At one year, the patient remains disease free with excellent spinal stability. Conclusion: Spinal surgeons may need to treat rare spinal tumors. Despite the proximity to neural and vascular structures, the goal of surgery is always a radical resection due to high recurrence rates.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

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Chondromyxoid fibroma of C1: first case report

et al. 2012

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“…Calcification is uncommon and occurs in 2% of lesions. 5 The classic histological features of CMF include a lobulated growth pattern with mixed chondroid, myxoid and fibrous areas. Cellular fibrous septae with higher cell concentration outline more sparsely cellular areas of myxoid and chondroid-like matrix.…”

Section: Chondromyxoid Fibromamentioning

confidence: 99%

Spinal chondromyxoid fibroma of C2

Bala

Robbins

Knuckey

et al. 2006

Journal of Clinical Neuroscience

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“…The tibia is the bone most frequently affected followed by the femur, foot and calcaneum. Occurrence in the upper limb is rare, but it has been described in the scapula [3], rib [6], sternum [14], pelvis [8,11], mandible [11] and occiput [9]. Reprint requests to: S. Baklouti, Service de Rhumatologie, C. H. U. H6di Chaker, 3029 Sfax, Tunisia …”

Section: Introductionmentioning

confidence: 99%