Chondrosarcomas of the facial region

Gallagher, T. M.; Strome, Marshall

doi:10.1288/00005537-197206000-00005

Cited by 49 publications

(26 citation statements)

References 2 publications

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“…Although radiation therapy is effective in some patients with various types of chondrosarcoma [2,5,7], radiation and chemotherapy should not be a first choice as a primary treatment modality. The value of palliativeness is yet to be determined [4,6,[10][11][12].…”

Section: Discussionmentioning

confidence: 99%

Primary Chondrosarcoma Arising in the Parotid Gland

Maruya¹,

Kurotaki

Fujita³

et al. 2001

ORL

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We report an extremely rare case of chondrosarcoma arising in the left parotid gland in a 45-year-old man who complained of painless swelling of the postauricular region. Computed tomography revealed a well-circumscribed tumor in the parotid area with a rim of scattered calcification. Under the diagnosis of benign parotid tumor, the tumor mass was removed with adequate margin. Histologic features were consistent with a low-grade chondrosarcoma showing lobular growth but clearly separated from adjacent glandular tissue of the parotid gland. Entire examination of the tumor disclosed no component of pleomorphic adenoma. There has been no evidence of recurrence for 2 months after the operation. The current case indicates that the parotid gland could be the site of occurrence of de novo primary chondrosarcoma.

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Section: Discussionmentioning

confidence: 99%

Primary Chondrosarcoma Arising in the Parotid Gland

Maruya¹,

Kurotaki

Fujita³

et al. 2001

ORL

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“…The majority of patients were in the 2nd, 3rd, 4th, and 5th decades of life, with a range of 2-89 years. At times Radiologically there is bone destruction characterized by single or multilocular osteolytic images, sometimes of a cystic but generally of an expansive nature [4,8,12,20,42,4648,50,55] accompanied in 25% of the cases, by the well-known "sun-ray'' image [ 14,[54][55][56][57]. Nortje et a1 [57] have studied the most important radiologic characteristics of chondrosarcomas, viz) increased opacity because of ossification; streaks in radiolucent areas; central areas of radiolucency, and fine subperiosteal spicules in the periphery.…”

Section: Discussionmentioning

confidence: 99%

“…No other therapeutic procedures have been utilized in the pathologic process under consideration, but mention should be made of cryosurgery as a modern procedure utilized by Gallagher et a1 [14].…”

Section: Discussionmentioning

confidence: 99%

“…No sex predilection is reported [8,4, although the statistics of the Mayo Clinic reported by Clark et al [5] indicate a predominance of males in a relation of 42:24. These sarcomas may appear at any age [8], the earliest reported being by Galagher et al [14] in a 16-month-old baby. Sat0 et a1 [12] reported one in a 3-year-old patient, while Hoffman et al [9] reported one in a patient 84 years old.…”

Section: Introductionmentioning

confidence: 99%

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Sarcomas of the jaw

Yoel¹,

Aguilar²,

Simkin³

et al. 1987

Seminars in Surgical Oncology

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A retrospective analysis is made of 61 patients with clinical and histological diagnosis of pure sarcomas of the jaw treated between 1950 and 1984. Surgery was the treatment of choice in 41 cases. Biopsy or palliative treatment were undertaken in the remaining patients. Twenty-four cases relapsed before 12 months, and 12 relapsed before 3 years. Twenty-four died before 12 months, nine before 2 years, and three after 2 years. At present there is no evidence of disease in eight patients: three out of 25 fibrosarcomas (one more than 1 year, one more than 13 years, and one more than 14 years), three out of 15 chondrosarcomas (one more than 1 year, one more than 13 years, and one more than 14 years), and two out of 15 osteosarcomas (one more than 18 years). The prognosis is gloomy. However, an early diagnosis and radical surgery contribute to an improvement in the course of the disease.

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“…Nodules demonstrate round to elongated cells set in mucoid matrix. Histological criteria for the proper diagnosis of this neoplasm is the presence of many cells with hyperchromatic nuclei, two or more such chondrocytes within a lacuna and gaint cell cartilage with the large single or multiple nuclei with clumps of chromatin and mitotic activity [7]. Lesion are graded 1-3 depending on amount and maturity of cartilage and anaplasticity of connective tissue.In Grade 2 and 3 areas of myxoid tissue and cystic degeneration are present consisting of proliferating plump chondroblast or spindle shaped mesenchymal cell and abnormal cartilage.…”

Section: Disscusionmentioning

confidence: 99%

Myxoid Chondrosarcoma of Nasomaxilloethmoid Region with Intracranial Extension

Sachdeva

2016

Indian J Otolaryngol Head Neck Surg

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Chondrosarcoma of the faciomaxillary area constitute only 4 % of non-epithelial tumours of the nasal cavity, paranasal sinuses and nasopharynx, making it one of the rare malignancy (Indian J Otolaryngol Head Neck Surg 60(3):284-286, [1]), with its myxoid variety still rarest. It is a slow-growing tumour, occurring mostly in middle-aged men. Primary chondrosarcoma of the nasal and paranasal sinus region, including the nasal septum, rarely extends into the cranial or intracranial areas unless there is recurrence (Indian J Ophthalmol 41(4):189-191, [2]. When it does occur, early diagnosis is difficult because patients generally present with common, nonspecific sinonasal complaints. A 45 year male patient came to ENT OPD with complaints of epistaxis, diplopia, facial swelling and loosening of teeth. On examination extensive swelling was present involving right maxilla, palate and ethmoid with shifting of Rt eye laterally. FNAC of swelling was non specific infected cystic lesion. On endoscopic examination there was erosion of Rt lateral wall of nose with mucoid material filling maxilla. Its wall was expanded & lined with velvety red mucosa. Maxillary antral biopsy report was myxoid chondrosarcoma. CT scan revealed extensive lesion of maxilla, ethmoid going up to optic nerve and brain. This case of myxoid chondrosarcoma is presented as it is a rare diagnosis. It presented with advanced disease involving nasomaxilloethmoid region and extended up to optic canal and middle cranial fossa. In a thorough review of Indian literature this was a rarely diagnosed tumour.

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Chondrosarcomas of the facial region

Cited by 49 publications

References 2 publications

Primary Chondrosarcoma Arising in the Parotid Gland

Primary Chondrosarcoma Arising in the Parotid Gland

Sarcomas of the jaw

Myxoid Chondrosarcoma of Nasomaxilloethmoid Region with Intracranial Extension

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