Chorioangioma of Placenta: A Rare Placental Cause for Adverse Fetal Outcome

Abstract

Chorioangioma is a benign angioma of placenta arising from chorionic tissue. Large chorioangioma has unfavourable effects on both mother and fetus. We describe a case with large chorioangioma that had a poor outcome on the fetus. We also reviewed the literature on prognostic factors affecting fetal outcome.

Giant chorioangioma of placenta: an infrequent placental cause for adverse feto-maternal outcome

“…Larger chorioangiomas (>5 cm), particularly when rapidly growing, are associated with negative clinical impact. 8,9 This consensus in literature about the association between the chorioangioma size and its clinical manifestations was replicated in our case.…”

Chorangioma- A Rare Cause for Polyhydramnios and Foetal Distress

“…1,2,7,8,14 The maternal complications are polyhydramnios, preeclampsia, antepartum haemorrhage, postpartum haemorrhage, premature rupture of membrane and obstructed labour. 2,14 Chorangioma should be considered as a cause for such conditions. Polyhydramnios is treated with amniocentesis and maternal indomethacin therapy.…”

“…Polyhydramnios is treated with amniocentesis and maternal indomethacin therapy. 2,14 The foetal complications can range from mild-to-severe anaemia, thrombocytopenia, cardiomegaly, hepatomegaly, disseminated intravascular coagulation, hydrops foetalis, growth retardation and various other congenital anomalies. 1,7,8,14 Our patient also presented with polyhydramnios and foetal distress, so was delivered promptly by caesarean section.…”

“…4,14 Acceleration of foetal lung maturity is brought about by steroid administration. 4,14 The final diagnosis was a large sized chorangioma associated with pregnancy disorder and foetal distress, however, unrelated with neonatal anomaly.…”

A Large Placental Chorioangioma without an Adverse Perinatal Effect

“…Large tumors are rare but those exceeding 5 cm in diameter may be associated with adverse effects on both mother and fetus which include intrauterine growth restriction, fetal anemia, thrombocytopenia, congestive heart failure, polyhydramnios, preterm labor, preeclampsia and sudden infant death (2)(3)(4)(5)(6)(7). The larger the size of the tumor the more is the chance of developing complications.…”