Choriocarcinoma with uterine rupture presenting as acute haemoperitoneum and shock

Abstract

Choriocarcinoma is a rare neoplasm and a malignant form of gestational trophoblastic disease. Invasive mole may perforate uterus through the myometrium resulting in uterine perforation and intraperitoneal bleeding. But uterine perforation due to choriocarcinoma is rare. We present a case of a young woman who presented 1 year after uterine evacuation of a molar pregnancy with invasive choriocarcinoma complicated by a uterine rupture and haemoperitoneum.

Choriocarcinoma with Uterine Rupture in a Patient with Confirmed COVID-19 Infection: A Rare Case Report

“…In hemodynamically stable patients, selective embolization of the main pelvic blood supply to the tumor can be performed by interventional radiology. Successful pregnancy after conservative surgery has also been reported (4,12,13).…”

“…CC should be suspected when there is persistent uterine bleeding following pregnancy. It is a rare neoplasm characterized by rapid growth, invasion into the myometrium, and distant metastasis (4,5). A theory of intratumoral bleeding suggests the invasion of trophoblastic cells into vessels leading to thrombosis, infarction, and formation of vascular aneurysms (5,6).…”

“…Emergency cases of active intraabdominal bleeding usually require hysterectomy as a lifesaving procedure (7)(8)(9). Fertility-sparing uterine lesion resection and uterine reconstruction for young women, who desire pregnancy, are preferred when the lesion is confined to the uterus without metastasis (4,7,10,11). In hemodynamically stable patients, selective embolization of the main pelvic blood supply to the tumor can be performed by interventional radiology.…”